Evidence map›Paper›PMID 39861255›Full record

ArticlePolymers2025

Acylase-Based Coatings on Sandblasted Polydimethylsiloxane-Based Materials for Antimicrobial Applications.

Cláudia A Silva, Joana Moreira, Marta Fernandes, Andrea Zille, Vanessa F Cardoso, Md Julker Nine, Filipe S Silva, Margarida M Fernandes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cláudia A SilvaCenter for Micro-Electro Mechanical Systems (CMEMS), Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-7279-7202
Joana MoreiraPhysics Centre of Minho and Porto Universities (CF-UM-UP), Campus Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-6438-3889
Marta Fernandes2C2T-Centre for Textile Science and Technology, Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-5814-415X
Andrea Zille2C2T-Centre for Textile Science and Technology, Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0001-5299-4164
Vanessa F CardosoCenter for Micro-Electro Mechanical Systems (CMEMS), Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-3039-5520
Md Julker NineCentre of Chemistry, Campus Gualtar, University of Minho, 4710-053 Braga, Portugal.ORCID 0000-0002-5740-8627
Filipe S SilvaCenter for Micro-Electro Mechanical Systems (CMEMS), Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.
Margarida M FernandesCenter for Micro-Electro Mechanical Systems (CMEMS), Campus Azurém, University of Minho, 4800-058 Guimarães, Portugal.ORCID 0000-0002-1529-3702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indwelling medical devices, such as urinary catheters, often experience bacterial colonization, forming biofilms that resist antibiotics and the host's immune defenses through quorum sensing (QS), a chemical communication system. This study explores the development of antimicrobial coatings by immobilizing acylase, a quorum-quenching enzyme, on sandblasted polydimethylsiloxane (PDMS) surfaces. PDMS, commonly used in medical devices, was sandblasted to increase its surface roughness, enhancing acylase attachment. FTIR analysis confirmed that acylase retained its three-dimensional structure upon immobilization, preserving its enzymatic activity. The antibacterial efficacy of the coatings was tested against

Indexed as

acylasePDMSquorum quenchingquorum sensingsandblasting

Identifiers

PMID39861255
PMCPMC11768103

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.