Evidence map›Paper›PMID 39861246›Full record

ArticlePolymers2025

Zinc Oxide Nanoparticle Loaded L-Carnosine Biofunctionalized Polyacrylonitrile Nanofibrous Wound Dressing for Post-Surgical Treatment of Melanoma.

Shahin Homaeigohar, Danial Kordbacheh, Sourav Banerjee, Jiacheng Gu, Yilong Zhang, Zhihong Huang

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahin HomaeigoharSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK.ORCID 0000-0003-2426-6690
Danial KordbachehSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK.
Sourav BanerjeeDivision of Cancer Research, School of Medicine, University of Dundee, Dundee DD1 9SY, UK.ORCID 0000-0003-2043-2989
Jiacheng GuSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK.
Yilong ZhangSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK.
Zhihong HuangSchool of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK.ORCID 0000-0003-4569-5400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofibrous dressing materials with an antitumor function can potentially inhibit recurrence of melanoma following the surgical excision of skin tumors. In this study, hydrolyzed polyacrylonitrile (hPAN) nanofibers biofunctionalized with L-carnosine (CAR) and loaded with bio (CAR)-synthesized zinc oxide (ZnO) nanoparticles, ZnO/CAR-hPAN (hereafter called ZCPAN), were employed to develop an antimelanoma wound dressing. Inspired by the formulation of the commercial wound healing Zn-CAR complex, i.e., polaprezinc (PLZ), for the first time, we benefitted from the synergy of zinc and CAR to create an antimelanoma nanofibrous wound dressing. According to scanning electron microscopy (SEM) images, ultrafine ZnO nanoparticles were homogenously distributed throughout the nanofibrous dressing. The ZCPAN nanofiber mat showed a significantly higher toughness (18.7 MJ.m

Indexed as

L-carnosine dipeptidemelanomapolyacrylonitrile nanofiberswound dressingzinc oxide nanoparticles

Identifiers

PMID39861246
PMCPMC11768544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.