Evidence map›Paper›PMID 39861186›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

2-Aminothiophene Derivatives-New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity.

Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Roberto Pontarolo, Julyanne Maria Saraiva de Sousa, Klinger Antonio da Franca Rodrigues, Marcus Tullius Scotti, Anuraj Nayarisseri and 2 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rodrigo Santos Aquino de AraújoLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.ORCID 0000-0002-2403-8746
Vitória Gaspar BernardoLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.
Robert da Silva TibúrcioLaboratory of Planning and Synthesis in Medicinal Chemistry, Pharmaceutical Sciences Department, Federal University of Pernambuco, Recife 50740-520, Brazil.
Danilo Cesar Galindo BedorPharmaceutical and Cosmetic Development Center (NUDFAC), Department of Pharmaceutical Science, Federal University of Pernambuco, Recife 50740-520, Brazil.ORCID 0000-0002-3901-9126
Michel Leandro de CamposHealth Sciences Institute, Federal University of Mato Grosso (UFMT), Sinop 78550-000, Brazil.ORCID 0000-0002-7147-7637
Roberto PontaroloDepartamento de Farmácia, Universidade Federal do Paraná, Av. Prefeito Lothário Meissner 632, Curitiba 80210-170, Brazil.ORCID 0000-0002-7049-4363
Julyanne Maria Saraiva de SousaInfectious Disease Laboratory, Campus Ministro Reis Velloso, Federal University of Parnaíba Delta, Parnaíba 64202-020, Brazil.
Klinger Antonio da Franca RodriguesDepartamento de Farmácia, Universidade Federal do Paraná, Av. Prefeito Lothário Meissner 632, Curitiba 80210-170, Brazil.ORCID 0000-0003-3904-3529
Marcus Tullius ScottiPostgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-4863-8057
Anuraj NayarisseriIn Silico Research Laboratory, Eminent Biosciences, Mahalakshmi Nagar, Indore 452010, India.ORCID 0000-0003-2567-9630
Pascal MarchandNantes Université, Cibles et médicaments des infections et de l'immunité, IICiMed, UR 1155, F-44000 Nantes, France.ORCID 0000-0001-7773-8642
Francisco Jaime Bezerra Mendonça-JuniorLaboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraíba, João Pessoa 58071-160, Brazil.ORCID 0000-0003-3588-833X

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior CAPES/COFECUB programCoordenação de Aperfeicoamento de Pessoal de Nível Superior finance code 001Fundação de Apoio à Pesquisa do Estado da Paraíba 030/2023Fundação de Apoio à Pesquisa do Estado da Paraíba 150859/2023-6National Council for Scientific and Technological Development 316996/2023-8National Council for Scientific and Technological Development 403260/2021-3
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2-aminothiophenebioisosterismdrug designleishmaniasispharmacomodulation

Identifiers

PMID39861186
PMCPMC11768359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.