Evidence map›Paper›PMID 39861162›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer's Disease: A Metabolomic and Proteomic Approach.

Huiling Wei, Tianyi Du, Weiwei Zhang, Wei Ma, Yao Yao, Juan Li

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huiling WeiSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China.
Tianyi DuSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China.
Weiwei ZhangSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China.
Wei MaSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China.
Yao YaoSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China.ORCID 0000-0001-7459-2107
Juan LiSchool of Pharmacy, Ningxia Medical University, Yinchuan 750004, China.

Funding

National Natural Science Foundation of China 82060792National Natural Science Foundation of China 82160759Natural Science Foundation of Ningxia 2024AAC02049Natural Science Foundation of Ningxia 2024AAC03294
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the leading cause of dementia among the elderly, yet effective treatments remain elusive. Total saikosaponins (TSS), the primary bioactive components in

Indexed as

Alzheimer’s diseasebiomarkersmetabolomicsproteomicssaikosaponins

Identifiers

PMID39861162
PMCPMC11768985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.