ArticlePharmaceuticals (Basel, Switzerland)2025
Optimization of the Antibacterial Activity of a Three-Component Essential Oil Mixture from Moroccan
Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Inefficacy ofAnimals : an open access journal from MDPI · 2026Article
- Optimization of an antifungal formulation based on eucalyptol, β-pinene, and α-terpinene against Candida albicans and Candida glabrata: A mixture design study.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Genoprotective Properties ofInternational journal of molecular sciences · 2026Article
- Optimization of Thyme, Cinnamon, and Black Seed Oil Combinations for Enhanced Antibacterial and Antioxidant Efficacy: Mixture Design and In Silico Insights.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Promising synergistic interactions and mixture optimization of safranal, crocin, and crocetin from MoroccanFrontiers in pharmacology · 2026Article
- Optimized formulation of a three-component extract mixture from Moroccan Crocus sativus L. (Stigmas, leaves, and Tepals) for enhanced antioxidant activity.Bioresources and bioprocessing · 2025Article
- Optimization of antibacterial and antifungal activities in Moroccan saffron by-products using mixture design and simplex centroid methodology.Scientific reports · 2025Article
- Optimization of Eugenol, Camphor, and Terpineol Mixture Using Simplex-Centroid Design for Targeted Inhibition of Key Antidiabetic Enzymes.Current issues in molecular biology · 2025Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
BACKGROUND/
objectivesThe rise of antibiotic-resistant pathogens has become a global health crisis, necessitating the development of alternative antimicrobial strategies. This study aimed to optimize the antibacterial effects of essential oils (EOs) from
methodsThis study utilized a simplex-centroid design to optimize the mixture ratios of EOs for maximal antibacterial and antioxidant effectiveness. The chemical profiles of the EOs were analyzed using gas chromatography-mass spectrometry (GC-MS). The antibacterial activity was assessed against
resultsThe optimized essential oil mixtures demonstrated potent antibacterial activity, with MIC values of 0.097% (
conclusionsThe study successfully demonstrates that optimized mixtures of EOs can serve as effective natural antibacterial agents. The findings highlight a novel approach to enhance the applications of essential oils, suggesting their potential use in food preservation and biopharmaceutical formulations. This optimization strategy offers a promising avenue to combat antibiotic resistance and enhance food safety using natural products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.