Evidence map›Paper›PMID 39861082›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of

Steven R Chamberlin, Jonathan A Zweig, Cody J Neff, Luke Marney, Jaewoo Choi, Liping Yang, Claudia S Maier, Amala Soumyanath, Shannon McWeeney, Nora E Gray

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Steven R ChamberlinDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA.
Jonathan A ZweigDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Cody J NeffDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Luke MarneyBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0001-8117-8246
Jaewoo ChoiBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Liping YangBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Claudia S MaierBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Amala SoumyanathDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-1569-6453
Shannon McWeeneyDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA.
Nora E GrayDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.

Funding

Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI GRAY, NORA · 2020 to 2024
$6.1M
Network models to capture multiple outcomes resulting from multi-component, salutogenic interventionsK08AT012477 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven Chamberlin · 2023 to 2026
$621k
Ultra-Performance Liquid Chromatography Tandem Quadrupole Mass Spectrometry SystemS10OD026922 · OD · OREGON STATE UNIVERSITY · PI MAIER, CLAUDIA S · 2019 to 2019
$577k
Triple Quadrupole/Linear Ion Trap LC-MS/MS for LPIS10RR027878 · NCRR · OREGON STATE UNIVERSITY · PI STEVENS, JAN FREDERIK · 2010 to 2010
$484k
NCCIH NIH HHS K08 AT012477NCCIH NIH HHS U19 AT010829NCCIH NIH HHS U19 AT010829, U19 AT010829-02S1NCRR NIH HHS S10 RR027878NIH HHS S10 OD026922
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

caffeoylquinic acidsCentella asiaticaco-expressionmetabolomemouse primary cortical neuronsomics integrationtranscriptometriterpenes

Identifiers

PMID39861082
PMCPMC11768890

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.