Evidence map›Paper›PMID 39860965›Full record

ArticlePathogens (Basel, Switzerland)2024

Therapeutic Drug Monitoring-Guided Linezolid Therapy for the Treatment of Multiple Staphylococcal Brain Abscesses in a 3-Month-Old Infant.

Anna Cascone, Maia De Luca, Raffaele Simeoli, Bianca Maria Goffredo, Laura Cursi, Costanza Tripiciano, Lorenza Romani, Stefania Mercadante, Martina Di Giuseppe, Francesca Ippolita Calo Carducci and 3 more

Abstract readCase Reports
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna CasconeResidency School of Pediatrics, Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0009-0005-1309-1639
Maia De LucaInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-7549-3514
Raffaele SimeoliDivision of Metabolic Diseases and Drug Biology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-3989-7703
Bianca Maria GoffredoDivision of Metabolic Diseases and Drug Biology, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Laura CursiInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Costanza TripicianoInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-6712-2334
Lorenza RomaniInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0003-4195-6626
Stefania MercadanteInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Martina Di GiuseppeInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Francesca Ippolita Calo CarducciInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-6087-8323
Davide LugliettoNeurosurgery Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-9744-3171
Paola BernaschiMicrobiology and Diagnostic Immunology Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Laura LancellaInfectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain abscesses are invasive infections of the central nervous system with a high level of treatment complexity especially in pediatric patients. Here, we describe a 3-month-old infant with multiple brain abscesses caused by methicillin-susceptible

Indexed as

Anti-Bacterial AgentsBrain AbscessDrug MonitoringLinezolidStaphylococcal InfectionsDrainageHumansInfantMaleStaphylococcus aureusTreatment OutcomeAnti-Bacterial AgentsLinezolidbrain abscesslinezolidmethicillin-sensitive Staphylococcus aureus (MSSA)multidisciplinary approachtherapeutic drug monitoring (TDM)

Identifiers

PMID39860965
PMCPMC11768877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.