Evidence map›Paper›PMID 39860781›Full record

ArticleSensors (Basel, Switzerland)2025

A Reusable Capillary Flow-Driven Microfluidic System for Abscisic Acid Detection Using a Competitive Immunoassay.

Cristiana Domingues, Marta S C Rodrigues, Pedro G M Condelipes, Ana Margarida Fortes, Virginia Chu, João Pedro Conde

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristiana DominguesInstituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.ORCID 0000-0003-1000-1181
Marta S C RodriguesInstituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.ORCID 0009-0009-5287-6294
Pedro G M CondelipesInstituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.
Ana Margarida FortesInstituto de Biossistemas e Ciências Integrativas (BioISI), Faculdade de Ciências de Lisboa, Universidade de Lisboa, 1749-016 Lisbon, Portugal.
Virginia ChuInstituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.ORCID 0000-0002-5306-4409
João Pedro CondeInstituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.ORCID 0000-0002-5677-3024

Funding

Fundação para a Ciência e a Tecnologia (FCT) 2020.09377.BDFundação para a Ciência e a Tecnologia (FCT) PD/BD/ 150393/2019Fundação para a Ciência e a Tecnologia (FCT) Project VineSense (PTDC/BAA-DIG/4735/2020) [http://doi.org/10.54499/PTDC/BAA-DIG/4735/2020]Fundação para a Ciência e a Tecnologia (FCT) Research Unit BIOISI (UID/MULTI/04046/2021)Fundação para a Ciência e a Tecnologia (FCT) Research Unit INESC MN BASE (UIDB/0536/2020) [doi: https://doi.org/10.54499/UIDB/05367/2020]Fundação para a Ciência e a Tecnologia (FCT) Research Unit INESC MN PROGRAMATICO (UIDP/0536/2020) [doi: https://doi.org/10.54499/UIDP/05367/2020]
6 · The paper itself

Abstract

Point-of-care (PoC) devices offer a promising solution for fast, portable, and easy-to-use diagnostics. These characteristics are particularly relevant in agrifood fields like viticulture where the early detection of plant stresses is crucial to crop yield. Microfluidics, with its low reagent volume requirements, is well-suited for such applications. Self-driven microfluidic devices, which rely on capillary forces for fluid motion, offer an attractive alternative by eliminating the need for external pumps and complex fluid control systems. However, traditional microfluidic prototyping materials like polydimethylsiloxane (PDMS) present challenges due to their hydrophobic nature. This paper presents the development of a reusable, portable, capillary-driven microfluidic platform based on a PDMS-PEG (polyethylene glycol) copolymer designed for the rapid low-cost detection of abscisic acid (ABA), a key biomarker for the onset of ripening of non-climacteric fruits and drought stress in vines. By employing passive fluid transport mechanisms, such as capillary-driven sequential flow, this platform enables precise biological and chemical screenings while maintaining portability and ease of use. A simplified field-ready sample processing method is used to prepare the grapes for analysis.

Indexed as

Abscisic AcidMicrofluidic Analytical TechniquesMicrofluidicsDimethylpolysiloxanesImmunoassayLab-On-A-Chip DevicesPolyethylene GlycolsAbscisic AcidbaysilonDimethylpolysiloxanesPolyethylene Glycolsabscisic acidcapillarityhydrophilic polydimethylsiloxane copolymer (PDMS-PEG)microfluidicsportability

Identifiers

PMID39860781
PMCPMC11768484

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.