Evidence map›Paper›PMID 39860780›Full record

ArticleSensors (Basel, Switzerland)2025

Opportunities and Challenges for Clinical Practice in Detecting Depression Using EEG and Machine Learning.

Damir Mulc, Jaksa Vukojevic, Eda Kalafatic, Mario Cifrek, Domagoj Vidovic, Alan Jovic

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Damir MulcUniversity Psychiatric Hospital Vrapče, Bolnička Cesta 32, 10000 Zagreb, Croatia.ORCID 0000-0002-4021-5378
Jaksa VukojevicUniversity Psychiatric Hospital Vrapče, Bolnička Cesta 32, 10000 Zagreb, Croatia.ORCID 0000-0003-4215-6743
Eda KalafaticUniversity of Zagreb Faculty of Electrical Engineering and Computing, Unska 3, 10000 Zagreb, Croatia.ORCID 0000-0001-6166-2225
Mario CifrekUniversity of Zagreb Faculty of Electrical Engineering and Computing, Unska 3, 10000 Zagreb, Croatia.ORCID 0000-0002-7554-0824
Domagoj VidovicUniversity Psychiatric Hospital Vrapče, Bolnička Cesta 32, 10000 Zagreb, Croatia.ORCID 0000-0002-1499-4355
Alan JovicUniversity of Zagreb Faculty of Electrical Engineering and Computing, Unska 3, 10000 Zagreb, Croatia.ORCID 0000-0003-3821-8091

Funding

Croatian Science Foundation IP-2022-10-8241
6 · The paper itself

Abstract

Major depressive disorder (MDD) is associated with substantial morbidity and mortality, yet its diagnosis and treatment rates remain low due to its diverse and often overlapping clinical manifestations. In this context, electroencephalography (EEG) has gained attention as a potential objective tool for diagnosing depression. This study aimed to evaluate the effectiveness of EEG in identifying MDD by analyzing 140 EEG recordings from patients diagnosed with depression and healthy volunteers. Using various machine learning (ML) classification models, we achieved up to 80% accuracy in distinguishing individuals with MDD from healthy controls. Despite its promise, this approach has limitations. The variability in the clinical and biological presentations of depression, as well as patient-specific confounding factors, must be carefully considered when integrating ML technologies into clinical practice. Nevertheless, our findings suggest that an EEG-based ML model holds potential as a diagnostic aid for MDD, paving the way for further refinement and clinical application.

Indexed as

DepressionElectroencephalographyMachine LearningMajor Depressive DisorderAdultFemaleHumansMaleMiddle Ageddepression detectionelectroencephalographymachine learningmajor depressive disorder

Identifiers

PMID39860780
PMCPMC11769153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.