Evidence map›Paper›PMID 39860540›Full record

ReviewJournal of clinical medicine2025

Periocular Aging Across Populations and Esthetic Considerations: A Narrative Review.

Brendan K Tao, Fahad R Butt, Thanansayan Dhivagaran, Michael Balas, Navdeep Nijhawan, Georges Nassrallah, Ahsen Hussain, Edsel B Ing

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brendan K TaoFaculty of Medicine, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0001-7069-3162
Fahad R ButtSchulich School of Medicine & Dentistry, University of Western Ontario, London, ON N6A 5C1, Canada.ORCID 0009-0004-1025-4765
Thanansayan DhivagaranSchulich School of Medicine & Dentistry, University of Western Ontario, London, ON N6A 5C1, Canada.ORCID 0000-0003-0571-2894
Michael BalasDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON M5T 3A9, Canada.ORCID 0000-0002-5948-0331
Navdeep NijhawanDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON M5T 3A9, Canada.ORCID 0009-0007-1571-9850
Georges NassrallahDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON M5T 3A9, Canada.
Ahsen HussainDepartment of Ophthalmology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Edsel B IngDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON M5T 3A9, Canada.ORCID 0000-0003-0623-0934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the face ages, the skin, fat, muscle, and fascia descend, and the underlying bone, cartilage, and teeth may lose mass. Oculofacial aging is a multifactorial process that is influenced by genetic, environmental, and lifestyle factors. This review summarizes the patterns of oculofacial aging that are observed across populations, including variations in periorbital hollowing, eyelid ptosis, and skin elasticity. Evidence indicates significant variability in aging patterns between sex- and race-based subgroups. Nonetheless, there remains a paucity of research on the progression of aging in some under-studied demographic groups. Signs of oculofacial aging often become apparent to patients well before these changes reach full maturity in later years, leading many to seek early esthetic interventions. Others may present with more advanced signs of aging, motivating a diverse range of therapeutic options. We discuss minimally invasive esthetic interventions to mitigate the signs of aging, which may include botulinum toxin injections, dermal fillers, applied energy-based treatments (e.g., lasers), and emerging techniques such as micro-focused ultrasound and platelet-rich plasma therapies. We review evidence on outcomes related to patient satisfaction and quality of life following esthetic interventions for oculofacial aging. Finally, we outline ethical considerations and challenges faced with the delivery of esthetic surgery, including treatment complications and the influence of social media. This review provides a comprehensive overview of oculofacial aging patterns, its management, and important considerations for the provision of esthetic oculofacial treatment.

Indexed as

agingdiversity equity inclusionestheticsminimally invasive proceduresoculofacial surgeryoculoplastic surgery

Identifiers

PMID39860540
PMCPMC11765755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.