Evidence map›Paper›PMID 39860533›Full record

ReviewJournal of clinical medicine2025

Carmen Rîpă, Roxana Gabriela Cobzaru, Miruna Raluca Rîpă, Alexandra Maștaleru, Andra Oancea, Carmen Marinela Cumpăt, Maria Magdalena Leon

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Global Review onInfectious disease reports · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carmen RîpăDepartment of Microbiology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", Universitatii Street No. 16, 700115 Iasi, Romania.
Roxana Gabriela CobzaruDepartment of Microbiology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", Universitatii Street No. 16, 700115 Iasi, Romania.
Miruna Raluca RîpăUniversity of Medicine and Pharmacy "Grigore T. Popa", Universitătii Street No. 16, 700115 Iasi, Romania.
Alexandra MaștaleruDepartment of Medical Specialties I, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-0008-9696
Andra OanceaDepartment of Medical Specialties I, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0003-1356-9581
Carmen Marinela CumpătClinical Rehabilitation Hospital, 700661 Iasi, Romania.ORCID 0000-0002-2564-537X
Maria Magdalena LeonDepartment of Medical Specialties I, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMATERIALS AND

methodsTwo independent reviewers used " KEY

findingsThis review included 52 case report articles, 17 from the USA, eight from India, seven from China, four from Pakistan, two from the UK, and one each from Thailand, Korea, Japan, Italy, Iran, Norway, Turkey, Costa Rica, Zambia, Australia, Taiwan, and Venezuela, and Mexico. This study included 98 patients, with 17 women (17.4%) and 81 men (82.6%). The cases presented in this study show that waiting to start treatment until a diagnosis is confirmed can lead to rapid worsening and bad outcomes, especially since there is currently no drug that works very well as a treatment and the death rate is around 98%. LIMITATIONS: The lack of case presentation standardization may lead to incomplete case information in the review since the cases did not follow a writing protocol. The small number of global cases may also lead to misleading generalizations, especially about these patients' treatment. Due to the small number of cases, there is no uniform sample of patients, making it difficult to determine the exact cause of infection.

Indexed as

case reportcontaminated waterNaegleria fowleri

Identifiers

PMID39860533
PMCPMC11765897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.