Evidence map›Paper›PMID 39860281›Full record

ArticleMolecules (Basel, Switzerland)2025

Thiamine and Thiamine Pyrophosphate as Non-Competitive Inhibitors of Acetylcholinesterase-Experimental and Theoretical Investigations.

Łukasz Szeleszczuk, Dariusz Maciej Pisklak, Błażej Grodner

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. BPC-157 and Its Novel Hybrid Analogs as Inhibitors of Acetylcholinesterase.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Exploring Nepicastat Activity: Beyond DβH.International journal of molecular sciences · 2025
    Article
  7. Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Łukasz SzeleszczukDepartment of Organic and Physical Chemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.ORCID 0000-0002-5302-3797
Dariusz Maciej PisklakDepartment of Organic and Physical Chemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Błażej GrodnerChair and Department of Biochemistry and Pharmacogenomics, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.ORCID 0000-0003-2184-6796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin B

Indexed as

AcetylcholinesteraseCholinesterase InhibitorsThiamineThiamine PyrophosphateHumansMolecular Docking SimulationMolecular Dynamics SimulationAcetylcholinesteraseCholinesterase InhibitorsThiamineThiamine Pyrophosphateacetylcholinesteraseacetylcholinesterase inhibitorsnon-competitive inhibitionthiaminethiamine pyrophosphate

Identifiers

PMID39860281
PMCPMC11767939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.