Evidence map›Paper›PMID 39860060›Full record

ArticleLife (Basel, Switzerland)2025

Factors Influencing the Choice Between Multi-Target Stool DNA and Colonoscopy for Colorectal Cancer Screening Among Alaska Native Peoples.

Lauren A Jeffries, Christie A Flanagan, Lila J Finney Rutten, John B Kisiel, Diana G Redwood

Registry-linked trialAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04336397 (Randomized Controlled Trial of the Stool DNA Test to Improve Colorectal Cancer Screening Among Alaska Native People), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04336397 nacompletednot on this map

Randomized Controlled Trial of the Stool DNA Test to Improve Colorectal Cancer Screening Among Alaska Native People

TypeinterventionalSponsorAlaska Native Tribal Health ConsortiumRan2021 to 2024Enrolled2,029ConditionsColorectal CancerArmsMulti-target stool DNA test, Colonoscopy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Colorectal Cancer in the American Indian and Alaska Native Community: A Holistic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lauren A JeffriesAlaska Native Tribal Health Consortium, 3900 Ambassador Dr., Anchorage, AK 99508, USA.
Christie A FlanaganAlaska Native Tribal Health Consortium, 3900 Ambassador Dr., Anchorage, AK 99508, USA.ORCID 0000-0002-1415-6167
Lila J Finney RuttenMayo Clinic, 200 1st St SW, Rochester, MN 55905, USA.
John B KisielMayo Clinic, 200 1st St SW, Rochester, MN 55905, USA.ORCID 0000-0002-3840-5324
Diana G RedwoodAlaska Native Tribal Health Consortium, 3900 Ambassador Dr., Anchorage, AK 99508, USA.ORCID 0000-0003-0360-5729

Funding

Randomized controlled trial of the stool DNA test to improve colorectal cancer screening among Alaska Native peopleR01CA247642 · NCI · ALASKA NATIVE TRIBAL HEALTH CONSORTIUM · PI REDWOOD, DIANA · 2020 to 2024
$1.9M
National Institutes of Health National Cancer Institute R01CA247642NCI NIH HHS R01 CA247642
6 · The paper itself

Abstract

The Alaska Tribal Health System is increasing colorectal cancer (CRC) screening among Alaska Native (AN) peoples, who experience the highest CRC rate in the world. Through a clinical trial (NCT04336397), AN people living in rural/remote Alaska were offered either the previously unavailable multi-target stool DNA test (mt-sDNA; Cologuard

Indexed as

Alaska Nativecancer screeningcolorectal cancercolorectal neoplasms/prevention and controlearly detection of cancerhealth carescreening barrierssurveys and questionnaires

Identifiers

PMID39860060
PMCPMC11767093

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.