Evidence map›Paper›PMID 39859975›Full record

ReviewLife (Basel, Switzerland)2024

Role of Coagulation Factors in Hepatocellular Carcinoma: A Literature Review.

Azeem Azam, Aleksandra Klisic, Filiz Mercantepe, Hamza Faseeh, Tolga Mercantepe, Saira Rafaqat

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Azeem AzamInstitute of Zoology, University of the Punjab, Lahore 54590, Pakistan.
Aleksandra KlisicFaculty of Medicine, University of Montenegro, 81000 Podgorica, Montenegro.ORCID 0000-0001-7870-0996
Filiz MercantepeDepartment of Endocrinology and Metabolism, Faculty of Medicine, Recep Tayyip Erdogan University, Rize 53200, Türkiye.ORCID 0000-0002-4325-1534
Hamza FaseehDepartment of Zoology, Govt. Islamia Graduate College Civil Lines, Lahore 54000, Pakistan.
Tolga MercantepeDepartment of Histology, Faculty of Medicine, Recep Tayyip Erdogan University, Rize 53200, Türkiye.ORCID 0000-0002-8506-1755
Saira RafaqatDepartment of Zoology, Lahore College for Women University, Lahore 44444, Pakistan.ORCID 0000-0001-7177-5602

Funding

The Recep Tayyip Erdogan University Development Foundation 02024010024138
6 · The paper itself

Abstract

Hepatocyte carcinoma (HCC) is a globally prevalent neoplasm with profound effects on morbidity and mortality rates. This review summarizes the complex interactions between coagulation abnormalities and the pathophysiological mechanisms underlying HCC. Essential coagulation biomarkers, such as P-selectin, thrombomodulin, d-dimer, prothrombin, and von Willebrand factor, are reviewed for their diagnostic, prognostic, and therapeutic significance. The contribution of these biomarkers to tumor progression, metastatic spread, and patient prognosis is highlighted through a synthesis of contemporary research findings. In addition, this review highlights the underlying mechanisms linking coagulation pathways to HCC pathogenesis and explores potential therapeutic targets. An integrative perspective on the role of coagulation markers in HCC may improve clinical management strategies for patients affected by this malignancy.

Indexed as

coagulation factorshepatocellular carcinomapathophysiology

Identifiers

PMID39859975
PMCPMC11766868

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.