Evidence map›Paper›PMID 39859963›Full record

ArticleLife (Basel, Switzerland)2024

Black Chokeberry (

Elena Daskalova, Mina Pencheva, Slavi Delchev, Lyudmila Vladimirova-Kitova, Spas Kitov, Stoyan Markov, David Baruh, Petko Denev

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elena DaskalovaDepartment of Anatomy, Histology and Embryology, Medical Faculty, Medical University, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-6661-0747
Mina PenchevaDepartment of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-0411-2291
Slavi DelchevDepartment of Anatomy, Histology and Embryology, Medical Faculty, Medical University, 4000 Plovdiv, Bulgaria.ORCID 0000-0001-8607-6986
Lyudmila Vladimirova-KitovaI-st Department of Internal Diseases, Cardiology Section Medical Faculty, Medical University, 4000 Plovdiv, Bulgaria.
Spas KitovI-st Department of Internal Diseases, Cardiology Section Medical Faculty, Medical University, 4000 Plovdiv, Bulgaria.
Stoyan MarkovDepartment of Otorhinolaryngology, Medical Faculty, Medical University, 4000 Plovdiv, Bulgaria.
David BaruhDepartment of Software Engineering, Faculty of Mathematics and Informatics, Sofia University "St. Kliment Ohridski", 1504 Sofia, Bulgaria.
Petko DenevInstitute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Laboratory of Biologically Active Substances, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-2290-791X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac aging is associated with myocardial remodeling and reduced angiogenesis. Counteracting these changes with natural products is a preventive strategy with great potential. The aim of this study was to evaluate the effect of

methodsHealthy male Wistar rats (n = 24) were divided into three groups: (1) young controls (CY)-age 2 months; (2) old controls (CO)-age 27 months; (3) AMJ group-27-month-old animals, supplemented with

resultsA higher vascular and capillary density was found in the hearts of the AMJ group, as compared to CO. The mean number of CD34+ cells in the myocardium increased by 18.6% in the AMJ group, as compared to CO (

conclusionsAs a result of the application of AMJ, noticeable neovascularization was found, which indicates improved myocardial nourishment. The present study demonstrates for the first time that polyphenol-rich AMJ can positively influence age-related microvascular myocardial remodeling in rats, thus outlining its potential as a preventive agent for healthy cardiac aging.

Indexed as

ACE2ageing heartblack chokeberry (Aronia melanocarpa)CD34neovascularization

Identifiers

PMID39859963
PMCPMC11766457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.