Evidence map›Paper›PMID 39859505›Full record

ArticleInternational journal of molecular sciences2025

Poliprotect

Mohamad Khalil, Valeria Perniola, Elisa Lanza, Laura Mahdi, Pierluca Sallustio, Valeria Idone, Daniela Semeraro, Maria Mastrodonato, Mario Testini, Jean-Francois Desaphy and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Natural Compounds for Counteracting GI and Liver Diseases.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamad KhalilClinica Medica "Augusto Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.
Valeria PerniolaClinica Medica "Augusto Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.
Elisa LanzaClinica Medica "Augusto Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.
Laura MahdiClinica Medica "Augusto Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.
Pierluca SallustioDivision of General Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.
Valeria IdoneAboca S.p.A, Sansepolcro, Italy.
Daniela SemeraroDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0003-4447-3910
Maria MastrodonatoDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0002-0799-8032
Mario TestiniDivision of General Surgery, Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-9297-4894
Jean-Francois DesaphySection of Pharmacology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0001-8816-9369
Piero PortincasaClinica Medica "Augusto Murri", Department of Precision and Regenerative Medicine and Ionian Area (DiMePrev-J), University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0001-5359-1471

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integrity of esophageal epithelial cells in patients with gastroesophageal reflux disease (GERD) or GERD-like symptoms is the first mechanism of protection to decrease the sensitivity to gastric reflux and heartburn symptoms. We investigated the protective effects of Poliprotect

Indexed as

Esophageal MucosaEsophagusProtective AgentsCaco-2 CellsElectric ImpedanceGastroesophageal RefluxHumansHydrogen PeroxideOxidative StressHydrogen PeroxideProtective Agentselectrophysiological protectionesophageal mucosal integritygastroesophageal reflux diseasemedical device made of substancessynergistic molecular complexUssing chambers

Identifiers

PMID39859505
PMCPMC11765600

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.