Evidence map›Paper›PMID 39859503›Full record

ArticleInternational journal of molecular sciences2025

Nicking Activity of M13 Bacteriophage Protein 2.

Esma Aybakan, Tanil Kocagoz, Ozge Can

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esma AybakanDepartment of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Türkiye.ORCID 0000-0002-4742-4914
Tanil KocagozDepartment of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Türkiye.
Ozge CanDepartment of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Türkiye.

Funding

Health Institutes of Türkiye (TUSEB), TUSEB- Group D R&D Project Call Project No: 32529Turkish Scientific and Technical Research Council (TUBITAK) "2244-Industrial Ph.D. Fellowship Program 119C136
6 · The paper itself

Abstract

Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication. This study was conducted to address the limitations of previous experiments, improve methodologies, and precisely determine the biochemical activity conditions of the P2 enzyme in vitro. For these purposes, the gene encoding P2 was cloned in

Indexed as

Bacteriophage M13Viral ProteinsDNA ReplicationDNA, SuperhelicalDNA, ViralEscherichia coliGreen Fluorescent ProteinsPlasmidsReplication OriginDNA, SuperhelicalDNA, ViralGreen Fluorescent ProteinsViral ProteinsM13 bacteriophage p2nicking enzymenicking reactionP2 cloningsingle-strand DNA viruses

Identifiers

PMID39859503
PMCPMC11765958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.