Evidence map›Paper›PMID 39859486›Full record

ArticleInternational journal of molecular sciences2025

Neurobehavioral Outcomes Relate to Activation Ratio in Female Carriers of Fragile X Syndrome Full Mutation: Two Pediatric Case Studies.

Elisa Di Giorgio, Silvia Benavides-Varela, Annamaria Porru, Sara Caviola, Marco Lunghi, Paola Rigo, Giovanna Mioni, Giulia Calignano, Martina Annunziata, Eloisa Valenza and 7 more

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Elisa Di GiorgioDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-1094-2363
Silvia Benavides-VarelaDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-4818-7372
Annamaria PorruDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-9896-1648
Sara CaviolaDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.
Marco LunghiDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-5747-4491
Paola RigoDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-4525-6267
Giovanna MioniDepartment of General Psychology, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-1212-4591
Giulia CalignanoDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-2913-8770
Martina AnnunziataDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.
Eloisa ValenzaDepartment of Developmental Psychology and Socialisation, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-2570-7128
Valentina LianiDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.
Federica BeghettiDepartment of Information Engineering, University of Padova, 35131 Padova, Italy.ORCID 0009-0002-2549-2147
Fabiola SpolaorDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-4723-0546
Elisa BettellaNeurodevelopment Molecular Genetics Laboratory, Department of Women's and Children's Health, University of Padova, 35127 Padova, Italy.
Roberta PolliNeurodevelopment Molecular Genetics Laboratory, Department of Women's and Children's Health, University of Padova, 35127 Padova, Italy.ORCID 0000-0002-7169-7111
Zimi SawachaDepartment of Information Engineering, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-2624-5415
Alessandra MurgiaDepartment of Women's and Children's Health, University of Padova, 35128 Padova, Italy.ORCID 0000-0001-6788-0653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder that causes a range of developmental problems including cognitive and behavioral impairment and learning disabilities. FXS is caused by full mutations (FM) of the

Indexed as

Fragile X Messenger Ribonucleoprotein 1Fragile X SyndromeMutationChildFemaleHeterozygoteHumansNeuropsychological TestsPhenotypeFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1activation ratioFragile X syndromefull mutationmulti-method research protocolneurobehavioral outcome

Identifiers

PMID39859486
PMCPMC11766333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.