Evidence map›Paper›PMID 39859428›Full record

ArticleInternational journal of molecular sciences2025

Targeting Bacterial Cell Division with Benzodioxane-Benzamide FtsZ Inhibitors as a Novel Strategy to Fight Gram-Positive Ovococcal Pathogens.

Berenice Furlan, Marta Sobrinos-Sanguino, Marcella Sammartino, Begoña Monterroso, Silvia Zorrilla, Alessia Lanzini, Lorenzo Suigo, Ermanno Valoti, Orietta Massidda, Valentina Straniero

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Berenice FurlanDipartimento di Biologia Cellulare e Integrata, Università degli Studi di Trento, Via Sommarive, 9, 38123 Trento, Italy.ORCID 0000-0002-3778-2240
Marta Sobrinos-SanguinoCentro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Marcella SammartinoCentro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.
Begoña MonterrosoInstituto de Química Física Blas Cabrera, Consejo Superior de Investigaciones Científicas, Serrano 119, 28006 Madrid, Spain.ORCID 0000-0003-2538-084X
Silvia ZorrillaCentro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.ORCID 0000-0002-6309-9058
Alessia LanziniDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milan, Italy.ORCID 0009-0009-0178-4541
Lorenzo SuigoDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milan, Italy.ORCID 0000-0002-8958-1547
Ermanno ValotiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milan, Italy.ORCID 0000-0002-5608-3875
Orietta MassiddaDipartimento di Biologia Cellulare e Integrata, Università degli Studi di Trento, Via Sommarive, 9, 38123 Trento, Italy.ORCID 0000-0001-8823-2372
Valentina StranieroDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milan, Italy.ORCID 0000-0002-5089-0879

Funding

MICIU/AEI/10.13039/501100011033 PID2019-104544GB-I00MICIU/AEI/10.13039/501100011033 PID2022-136951NB-I00MICIU/AEI/10.13039/501100011033 PTA2020-018219-I
6 · The paper itself

Abstract

The widespread emergence of antimicrobial resistance (AMR) is a serious threat to global public health and among Gram-positive cocci,

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBenzamidesCell DivisionCytoskeletal ProteinsStreptococcus pneumoniaeMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial ProteinsBenzamidesCytoskeletal ProteinsFtsZ protein, Bacteriaantimicrobial resistancebacterial cell divisionbenzodioxane–benzamidesFtsZ inhibitorsnovel targetsStreptococcus pneumoniae

Identifiers

PMID39859428
PMCPMC11765573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.