Evidence map›Paper›PMID 39859373›Full record

ArticleInternational journal of molecular sciences2025

The Cell Polarity Protein MPP5/PALS1 Controls the Subcellular Localization of the Oncogenes

Marcell Tóth, Shan Wan, Jennifer Schmitt, Patrizia Birner, Teng Wei, Fabian von Bubnoff, Carolina de la Torre, Stefan Thomann, Federico Pinna, Peter Schirmacher and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcell TóthInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-6946-8192
Shan WanInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-2392-6733
Jennifer SchmittInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Patrizia BirnerInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Teng WeiInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Fabian von BubnoffInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0003-2274-7562
Carolina de la TorreNGS Core Facility, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.ORCID 0000-0001-8918-2266
Stefan ThomannInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-3500-0014
Federico PinnaInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-6815-110X
Peter SchirmacherInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Sofia Maria Elisabeth WeilerInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Kai BreuhahnInstitute of Pathology, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.

Funding

Deutsche Forschungsgemeinschaft 314905040Deutsche Forschungsgemeinschaft 414059188Physician-Scientist Program of Heidelberg University, Faculty of Medicine
6 · The paper itself

Abstract

The oncogenes yes-associated protein (

Indexed as

Adaptor Proteins, Signal TransducingCarcinoma, HepatocellularLiver NeoplasmsMembrane ProteinsTranscription FactorsCell Line, TumorCell NucleusCell PolarityGene Expression Regulation, NeoplasticHumansProtein BindingTranscriptional Coactivator with PDZ-Binding Motif ProteinsYAP-Signaling ProteinsAdaptor Proteins, Signal TransducingMembrane ProteinsTranscriptional Coactivator with PDZ-Binding Motif ProteinsTranscription FactorsWWTR1 protein, humanYAP1 protein, humanYAP-Signaling Proteinsapical polarityCrumbs complexHCCHippo pathwaytumor-suppressor gene

Identifiers

PMID39859373
PMCPMC11766031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.