Evidence map›Paper›PMID 39859336›Full record

ArticleInternational journal of molecular sciences2025

Viability and Radiosensitivity of Human Tumor Cells from Breast and Colon Are Influenced by

Linda Rebecca Haake, Ahmed El Menuawy, Hannes Rennau, Frank Marthe, Urs Hähnel, Felix Bock, Guido Hildebrandt, Katrin Manda

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linda Rebecca HaakeDepartment of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.
Ahmed El MenuawyInstitute for Breeding Research on Horticultural Crops, Julius Kühn Institute (JKI), Federal Research Centre for Cultivated Plants, Erwin-Baur-Strasse 27, 06484 Quedlinburg, Germany.
Hannes RennauDepartment of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.
Frank MartheInstitute for Breeding Research on Horticultural Crops, Julius Kühn Institute (JKI), Federal Research Centre for Cultivated Plants, Erwin-Baur-Strasse 27, 06484 Quedlinburg, Germany.ORCID 0000-0001-9025-7560
Urs HähnelInstitute for Breeding Research on Horticultural Crops, Julius Kühn Institute (JKI), Federal Research Centre for Cultivated Plants, Erwin-Baur-Strasse 27, 06484 Quedlinburg, Germany.
Felix BockDepartment of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.ORCID 0009-0001-5795-9509
Guido HildebrandtDepartment of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.ORCID 0000-0002-0498-2692
Katrin MandaDepartment of Radiotherapy and Radiation Oncology, University Medical Center Rostock, Suedring 75, 18059 Rostock, Germany.ORCID 0000-0002-6911-022X

Funding

University of Rostock no number
6 · The paper itself

Abstract

To enhance the treatment of tumors that are resistant to radio- and chemotherapy while minimizing the side effects of radiochemotherapy, researchers are continuously seeking new active compounds for use in combination with radiotherapy. Therefore, the aim of our study was to examine the cytotoxic and radiosensitizing effects of an extract from St. John's Wort (

Indexed as

Breast NeoplasmsColonic NeoplasmsHypericumPlant ExtractsRadiation-Sensitizing AgentsRadiation ToleranceCell Line, TumorCell ProliferationCell SurvivalDNA Breaks, Double-StrandedFemaleHT29 CellsHumansMCF-7 CellsPlant ExtractsRadiation-Sensitizing Agentsclonogenic survivalHT-29Hypericumionizing radiationMCF-7St. John’s Wort

Identifiers

PMID39859336
PMCPMC11765585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.