Evidence map›Paper›PMID 39859311›Full record

ArticleInternational journal of molecular sciences2025

New Brusatol Derivatives as Anti-Settlement Agents Against Barnacles, Targeting HSP90: Design, Synthesis, Biological Evaluation, and Molecular Docking Investigations.

Wang Jiang, Tongtong Luan, Pei Cao, Zhonghui Ma, Zhiwei Su

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wang JiangCollege of Agriculture, Guangxi University, Nanning 530004, China.ORCID 0009-0005-0897-0073
Tongtong LuanInstitute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Pei CaoInstitute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.ORCID 0000-0002-2298-4667
Zhonghui MaCollege of Agriculture, Guangxi University, Nanning 530004, China.
Zhiwei SuCollege of Agriculture, Guangxi University, Nanning 530004, China.

Funding

National Natural Science Foundation of China 32060098National Natural Science Foundation of China 32260047Natural Science Foundation of Guangxi Province 2018GXNSFAA281146Natural Science Foundation of Guangxi Province 2023GXNSFAA026346Natural Science Foundation of Guangxi Province 2023GXNSFBA026297
6 · The paper itself

Abstract

The increasing challenge of marine biofouling, mainly due to barnacle settlement, necessitates the development of effective antifoulants with minimal environmental toxicity. In this study, fifteen derivatives of brusatol were synthesized and characterized using

Indexed as

HSP90 Heat-Shock ProteinsThoracicaAnimalsBiofoulingDrug DesignMolecular Docking SimulationStructure-Activity RelationshipZebrafishHSP90 Heat-Shock Proteinsantifoulingbarnaclebrusatolderivativesmolecular docking

Identifiers

PMID39859311
PMCPMC11765156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.