Evidence map›Paper›PMID 39859284›Full record

ArticleInternational journal of molecular sciences2025

Enhancing the Solubility and Dissolution of Apigenin: Solid Dispersions Approach.

Natalia Rosiak, Ewa Tykarska, Andrzej Miklaszewski, Robert Pietrzak, Judyta Cielecka-Piontek

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalia RosiakDepartment of Pharmacognosy and Biomaterials, Faculty of Pharmacy, Poznan University of Medical Sciences, 3 Rokietnicka St., 60-806 Poznan, Poland.ORCID 0000-0003-4722-6413
Ewa TykarskaDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, 3 Rokietnicka St., 60-806 Poznan, Poland.ORCID 0000-0001-9393-3536
Andrzej MiklaszewskiFaculty of Materials Engineering and Technical Physics, Institute of Materials Science and Engineering, Poznan University of Technology, 60-965 Poznan, Poland.ORCID 0000-0001-6792-4281
Robert PietrzakFaculty of Chemistry, Adam Mickiewicz University, 8 Uniwersytetu Poznańskiego St., 61-614 Poznan, Poland.
Judyta Cielecka-PiontekDepartment of Pharmacognosy and Biomaterials, Faculty of Pharmacy, Poznan University of Medical Sciences, 3 Rokietnicka St., 60-806 Poznan, Poland.ORCID 0000-0003-0891-5419

Funding

Narodowym Centrum Nauki 2020/37/B/NZ7/03975
6 · The paper itself

Abstract

Apigenin (APG), a bioactive flavonoid with promising therapeutic potential, suffers from poor water solubility, which limits its bioavailability. To address this, solid dispersions of APG were prepared using ball milling with sodium alginate (SA), Pluronic

Indexed as

ApigeninAlginatesAntioxidantsDrug CompoundingDrug LiberationDrug StabilityExcipientsHydrogen-Ion ConcentrationPoloxamerSolubilitySpectroscopy, Fourier Transform InfraredAlginatesAntioxidantsApigeninExcipientsPoloxamerapigeninFT-IRsolid dispersionsolubility

Identifiers

PMID39859284
PMCPMC11766082

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.