Evidence map›Paper›PMID 39859214›Full record

ArticleInternational journal of molecular sciences2025

Geon Ko, Jinho Kim, Yongjae Hong, Yeong-Jae Jeon, Hyun-Man Baek, Donghun Lee, Keun-A Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Protective effects ofFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Geon KoDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.ORCID 0009-0006-0442-5796
Jinho KimDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0002-2631-5049
Yongjae HongDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.
Yeong-Jae JeonDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.
Hyun-Man BaekDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.
Donghun LeeDepartment of Herbal Pharmacology, College of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0000-0003-1075-0713
Keun-A ChangDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Science & Technology, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0002-6157-6340

Funding

Gachon University research fund of 2022 GCU-202206140001National Research Foundation (NRF) of Korea 2020M3A9E4104384
6 · The paper itself

Abstract

Ischemic stroke, caused by blocked cerebral blood flow, requires prompt intervention to prevent severe motor and cognitive impairments. Despite extensive drug development efforts, the failure rate of clinical trials remains high, highlighting the need for novel therapeutic approaches. This study investigated the therapeutic potential of a natural herbal extract mixture of

Indexed as

Astragalus PlantIschemic StrokeNLR Family, Pyrin Domain-Containing 3 ProteinPlant ExtractsPyroptosisScutellaria baicalensisAnimalsDisease Models, AnimalInfarction, Middle Cerebral ArteryMaleMiceMice, Inbred C57BLSignal TransductionNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousePlant ExtractsScutellaria baicalensis extractAstragalus mongholicusEAHMinflammationischemic strokemiddle cerebral artery occlusionpyroptosisScutellaria baicalensis

Identifiers

PMID39859214
PMCPMC11765050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.