Evidence map›Paper›PMID 39859199›Full record

ReviewInternational journal of molecular sciences2025

Adhesion Mechanism, Applications, and Challenges of Ocular Tissue Adhesives.

Zuquan Hu, Xinyuan He, Lijing Teng, Xiangyu Zeng, Simian Zhu, Yu Dong, Zhu Zeng, Qiang Zheng, Xiaomin Sun

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zuquan HuKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.ORCID 0000-0003-4978-4363
Xinyuan HeKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.ORCID 0009-0009-3317-6399
Lijing TengKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.
Xiangyu ZengKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.
Simian ZhuKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.
Yu DongKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.
Zhu ZengKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.ORCID 0000-0003-0842-9402
Qiang ZhengKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.
Xiaomin SunKey Laboratory of Biology and Medical Engineering, School of Biology and Engineering (School of Modern Industry for Health and Medicine), Guizhou Medical University, Guiyang 550001, China.ORCID 0000-0001-6027-4722

Funding

Engineering center of Guizhou medical university [2024]002Guizhou Provincial Basic Research Program Z46032; ZK[2022]381; ZK[2021]475; ZK[2021]5637Guizhou Provincial Key Technology R&D Program 2024161Science Foundation of Guizhou Medical University 21NFSCP41; 20NFSP57The Excellent Young Talents Plan of Guizhou Medical University grant no. 2021-101The National Natural Science Foundation of China 32360235; 32460235; 12132006; 32371373The Science and Technology Fund of Guizhou Provincial Health Commission gzwkj2022-444; gzwkjxm2024-173The Youth Science and Technology Talents Growth Project of Guizhou Ordinary Colleges and Universities KY [2024]100
6 · The paper itself

Abstract

Corneal injury is prevalent in ophthalmology, with mild cases impacting vision and severe cases potentially resulting in permanent blindness. In clinical practice, standard treatments for corneal injury involve transplantation surgery combined with pharmacological therapy. However, surgical sutures exhibit several limitations, which can be overcome using tissue adhesives. With recent advances in biomedical materials, the use of ophthalmic tissue adhesives has expanded beyond wound closure, including tissue filling and drug delivery. Furthermore, the use of tissue adhesives has demonstrated promising outcomes in drug delivery, ophthalmic disease diagnosis, and biological scaffolds. This study briefly introduces common adhesion mechanisms and their applications in ophthalmology, aiming to increase interest in tissue adhesives and clinical ophthalmic treatment.

Indexed as

Corneal InjuriesTissue AdhesivesAnimalsDrug Delivery SystemsHumansTissue Adhesivescorneal repairmedical tissue adhesivewound closure

Identifiers

PMID39859199
PMCPMC11765468

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.