Evidence map›Paper›PMID 39859197›Full record

ArticleInternational journal of molecular sciences2025

Endothelial Dysfunction and Hemostatic System Activation in Relation to Shift Workers, Social Jetlag, and Chronotype in Female Nurses.

Gleb Saharov, Barbara Salti, Maram Bareya, Anat Keren-Politansky, Muhammed Fodi, Tamar Shochat, Yona Nadir

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Circadian clock regulation of hemostasis: a systematic review of molecular pathways.Research and practice in thrombosis and haemostasis · 2026
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gleb SaharovThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.ORCID 0009-0008-1640-6992
Barbara SaltiThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.ORCID 0009-0006-3408-0194
Maram BareyaThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.
Anat Keren-PolitanskyThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.
Muhammed FodiThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.
Tamar ShochatDepartment of Nursing, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa 3109601, Israel.ORCID 0000-0002-4371-3567
Yona NadirThrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian misalignment, due to shiftwork and/or individual chronotype and/or social jetlag (SJL), quantified as the difference between internal and social timing, may contribute to cardiovascular disease. Markers of endothelial dysfunction and activation of the coagulation system may predict cardiovascular pathology. The present study aim was to investigate the effects of shift work, SJL, and chronotype on endothelial function and coagulation parameters. One hundred female nurses underwent endothelial function testing using the EndoPAT and blood sampling for coagulation markers, repeated at 06:00-9:00 and 18:00-21:00. We found that compared with day workers, endothelial function and fibrinogen levels were lower (

Indexed as

Circadian RhythmEndothelium, VascularHemostasisJet Lag SyndromeNursesShift Work ScheduleAdultBiomarkersBlood CoagulationChronotypeFemaleGlucuronidaseHeparanaseHumansMiddle AgedPlasminogen Activator Inhibitor 1BiomarkersGlucuronidaseHeparanasePlasminogen Activator Inhibitor 1chronotypecoagulationendothelial dysfunctionshift workerssocial jetlag

Identifiers

PMID39859197
PMCPMC11764714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.