Evidence map›Paper›PMID 39859167›Full record

ArticleInternational journal of molecular sciences2025

A Multi-Omics Analysis of a Mitophagy-Related Signature in Pan-Cancer.

Nora Agir, Ilias Georgakopoulos-Soares, Apostolos Zaravinos

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nora AgirDepartment of Life Sciences, School of Sciences, European University Cyprus, Nicosia 1516, Cyprus.
Ilias Georgakopoulos-SoaresInstitute for Personalized Medicine, Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0003-3641-1488
Apostolos ZaravinosDepartment of Life Sciences, School of Sciences, European University Cyprus, Nicosia 1516, Cyprus.ORCID 0000-0003-4625-5562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitophagy, an essential process within cellular autophagy, has a critical role in regulating key cellular functions such as reproduction, metabolism, and apoptosis. Its involvement in tumor development is complex and influenced by the cellular environment. Here, we conduct a comprehensive analysis of a mitophagy-related gene signature, composed of

Indexed as

MitophagyNeoplasmsCell Cycle ProteinsDNA MethylationGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMembrane Transport ProteinsMultiomicsMutationProtein KinasesPTEN-Induced Putative KinaseTranscriptomeTumor MicroenvironmentCell Cycle ProteinsMembrane Transport ProteinsOPTN protein, humanProtein KinasesPTEN-Induced Putative KinaseBECN1BNIP3Ldrug resistancedrug sensitivityMAP1LC3mitophagymulti-omicsOPTNpan-cancerPARK2PINK1PRKNSRC

Identifiers

PMID39859167
PMCPMC11765132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.