Evidence map›Paper›PMID 39859153›Full record

ArticleInternational journal of molecular sciences2025

Human Induced Lung Organoids: A Promising Tool for Cystic Fibrosis Drug Screening.

Anna Demchenko, Maxim Balyasin, Aleksandra Nazarova, Olga Grigorieva, Irina Panchuk, Ekaterina Kondrateva, Vyacheslav Tabakov, Olga Schagina, Elena Amelina, Svetlana Smirnikhina

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna DemchenkoLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Maxim BalyasinScientific and Educational Resource Center, Peoples' Friendship University of Russia, Miklukho-Maklaya, 6, 117198 Moscow, Russia.ORCID 0000-0002-3097-344X
Aleksandra NazarovaLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Olga GrigorievaLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Irina PanchukLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Ekaterina KondratevaLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Vyacheslav TabakovMoscow Branch of the Biobank "All-Russian Collection of Biological Samples of Hereditary Diseases", Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.
Olga SchaginaDNA-Diagnostics Laboratory, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.ORCID 0000-0003-4905-1303
Elena AmelinaLaboratory of Cystic Fibrosis, Research Institute of Pulmonology, 11th Parkovaya Str., 32/4, 105077 Moscow, Russia.ORCID 0000-0002-5356-9415
Svetlana SmirnikhinaLaboratory of Genome Editing, Research Centre for Medical Genetics, Moskvorechye, 1, 115522 Moscow, Russia.

Funding

Ministry of Science and Higher Education of the Russian Federation for RCMG None
6 · The paper itself

Abstract

Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the

Indexed as

Cystic FibrosisLungOrganoidsAminophenolsAminopyridinesBenzodioxolesCystic Fibrosis Transmembrane Conductance RegulatorDrug Evaluation, PreclinicalHumansInduced Pluripotent Stem CellsMutationQuinolonesAminophenolsAminopyridinesBenzodioxolesCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorivacaftorQuinolonesairway basal cellsCFTR modulatorscystic fibrosisforskolin-induced swelling assayhuman induced pluripotent stem cellslung organoids

Identifiers

PMID39859153
PMCPMC11764749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.