Evidence map›Paper›PMID 39859110›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Strategies for Optimizing Acute Burn Wound Therapy: A Comprehensive Review.

Andrei Cretu, Andreea Grosu-Bularda, Eliza-Maria Bordeanu-Diaconescu, Florin-Vlad Hodea, Vladut-Alin Ratoiu, Catalina-Stefania Dumitru, Mihaela-Cristina Andrei, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrei CretuDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0006-5348-7213
Andreea Grosu-BulardaDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-2943-2611
Eliza-Maria Bordeanu-DiaconescuClinic of Plastic Surgery and Reconstructive Microsurgery, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.ORCID 0009-0009-7205-1134
Florin-Vlad HodeaDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-9297-6769
Vladut-Alin RatoiuDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Catalina-Stefania DumitruDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mihaela-Cristina AndreiDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Tiberiu-Paul NeaguDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-4319-1965
Ioan LascarDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Cristian-Sorin HarigaDepartment 11, Discipline Plastic and Reconstructive Surgery, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-0965-9736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in acute burn wound therapy are transforming the management of burn injuries, with a focus on improving healing times, graft integration, and minimizing complications. However, current clinical treatments face significant challenges, including the difficulty of accurately assessing wound depth and tissue viability, which can lead to suboptimal treatment planning. Traditional closure methods often struggle with issues such as delayed wound closure, limited graft survival, inadequate tissue regeneration, and insufficient vascularization. Furthermore, managing infection and minimizing scarring remain persistent obstacles, impacting functional recovery and aesthetic outcomes. Key areas of innovation include advanced imaging techniques that enable more precise assessment of wound depth, size, and tissue viability, allowing for more accurate treatment planning. In addition, new closure strategies are being developed to accelerate wound closure, enhance graft survival, and address challenges such as tissue regeneration, vascularization, and infection prevention. These strategies aim to optimize both functional recovery and aesthetic outcomes, reducing scarring and improving the quality of life for burn patients. While promising, these emerging techniques require further research and clinical validation to refine their effectiveness and expand their accessibility. Together, these innovations represent a significant shift in acute burn care, offering the potential for more personalized, efficient, and effective treatments.

Indexed as

BurnsWound HealingCicatrixHumansburn woundimaging techniquesnovel therapiesskin substitutestherapeutic strategieswound healing

Identifiers

PMID39859110
PMCPMC11766551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.