Evidence map›Paper›PMID 39859053›Full record

ArticleMedicina (Kaunas, Lithuania)2025

Functional and Cognitive Impairment in Patients with Relapsing-Remitting Multiple Sclerosis: Cognitive Tests and Plasma Neurofilament Light Chain Levels.

Elina Polunosika, Joel Simren, Arta Akmene, Nikita Klimovskis, Kaj Blennow, Daina Pastare, Henrik Zetterberg, Renars Erts, Guntis Karelis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neurofilament Light Chain and Disability Measures as Predictors of Cognitive Decline in Early Multiple Sclerosis.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elina PolunosikaDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.
Joel SimrenDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 40530 Molndal, Sweden.
Arta AkmeneDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.
Nikita KlimovskisFaculty of Medicine, Riga Stradinš University, LV-1007 Riga, Latvia.
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 40530 Molndal, Sweden.
Daina PastareDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.ORCID 0000-0002-8056-7087
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 40530 Molndal, Sweden.
Renars ErtsFaculty of Medicine and Life Sciences, University of Latvia, LV-1050 Riga, Latvia.ORCID 0000-0003-3674-8822
Guntis KarelisDepartment of Neurology and Neurosurgery, Riga East University Hospital, LV-1038 Riga, Latvia.ORCID 0000-0002-9586-2775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cognitive DysfunctionMultiple Sclerosis, Relapsing-RemittingNeurofilament ProteinsAdultBiomarkersCross-Sectional StudiesDisability EvaluationFemaleHumansMaleMiddle AgedNeuropsychological TestsBiomarkersneurofilament protein LNeurofilament Proteins9-HPTBVMT-REDSSmultiple sclerosisneurofilamentpNfLSDMT

Identifiers

PMID39859053
PMCPMC11766462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.