Evidence map›Paper›PMID 39858965›Full record

ReviewMicroorganisms2025

Chronic Endometritis and Antimicrobial Resistance: Towards a Multidrug-Resistant Endometritis? An Expert Opinion.

Francesco Di Gennaro, Giacomo Guido, Luisa Frallonardo, Laura Pennazzi, Miriana Bevilacqua, Pietro Locantore, Amerigo Vitagliano, Annalisa Saracino, Ettore Cicinelli

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco Di GennaroClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza Giulio Cesare n. 11, Cap 70124 Bari, Italy.ORCID 0000-0003-3453-5647
Giacomo GuidoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza Giulio Cesare n. 11, Cap 70124 Bari, Italy.ORCID 0009-0004-8783-7221
Luisa FrallonardoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza Giulio Cesare n. 11, Cap 70124 Bari, Italy.ORCID 0009-0001-3897-9678
Laura PennazziStudio Ostetrico/Nutrizionale DeaLuce, Cap 00168 Rome, Italy.
Miriana BevilacquaClinic of Obstetrics & Gynaecology, University of "Aldo Moro", Cap 70124 Bari, Italy.
Pietro LocantoreUnit of Endocrinology, Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Fondazione Policlinico "A. Gemelli" IRCCS, Cap 00168 Rome, Italy.ORCID 0000-0002-4772-1417
Amerigo VitaglianoClinic of Obstetrics & Gynaecology, University of "Aldo Moro", Cap 70124 Bari, Italy.ORCID 0000-0002-2824-5435
Annalisa SaracinoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza Giulio Cesare n. 11, Cap 70124 Bari, Italy.
Ettore CicinelliClinic of Obstetrics & Gynaecology, University of "Aldo Moro", Cap 70124 Bari, Italy.ORCID 0000-0003-2390-4582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by abnormal infiltration of plasma cells into the endometrial stroma. Frequently associated with repeated implantation failure, recurrent pregnancy loss, and infertility, CE significantly impacts women's health, contributing to conditions such as abnormal uterine bleeding and endometriosis. Treatment typically involves antibiotic therapy; however, the efficacy of these treatments is increasingly compromised by the rise of antimicrobial resistance (AMR). This paper examines the critical links between AMR and CE, proposing strategies to enhance clinical management and optimize treatment outcomes.

Indexed as

antibiotic treatmentchronic endometritisfertilitymultidrug resistancepersistent chronic endometritis

Identifiers

PMID39858965
PMCPMC11767291

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.