Evidence map›Paper›PMID 39858953›Full record

ArticleMicroorganisms2025

Key Taxa of the Gut Microbiome Associated with the Relationship Between Environmental Sensitivity and Inflammation-Related Biomarkers.

Satoshi Takasugi, Shuhei Iimura, Miyabi Yasuda, Yoshie Saito, Masashi Morifuji

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Satoshi TakasugiR&D Division, Meiji Co., Ltd., 1-29-1 Nanakuni, Hachioji 192-0919, Japan.ORCID 0009-0005-2012-8532
Shuhei IimuraFaculty of Education, Soka University; 1-236 Tangi-machi, Hachioji 192-8577, Japan.ORCID 0000-0002-4410-187X
Miyabi YasudaWellness Science Labs, Meiji Holdings Co., Ltd., 1-29-1 Nanakuni, Hachioji 192-0919, Japan.
Yoshie SaitoWellness Science Labs, Meiji Holdings Co., Ltd., 1-29-1 Nanakuni, Hachioji 192-0919, Japan.ORCID 0000-0001-8122-3211
Masashi MorifujiWellness Science Labs, Meiji Holdings Co., Ltd., 1-29-1 Nanakuni, Hachioji 192-0919, Japan.ORCID 0000-0002-0195-4127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individual differences in environmental sensitivity are linked to stress-related psychiatric symptoms. In previous research, we found that high environmental sensitivity can be a risk factor for increased inflammation and gut permeability, particularly when gut microbiome diversity is low. However, the specific gut bacterial taxa involved in this interaction remain unclear. As a preliminary study, this research aimed to identify the key gut microbiome taxa associated with this relationship. Environmental sensitivity, gut microbiome composition, gut permeability (lipopolysaccharide-binding protein, LBP), and inflammation (C-reactive protein, CRP) biomarkers were evaluated in 88 participants. The interaction between environmental sensitivity and the relative abundance of the family

Indexed as

AkkermansiaButyricimonasCoprobacterenvironmental sensitivitygut barriergut-brain axisgut microbiomeinflammationsensory processing sensitivity

Identifiers

PMID39858953
PMCPMC11767568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.