Evidence map›Paper›PMID 39858951›Full record

ArticleMicroorganisms2025

Bloodstream Infections in Critical Care Units in England, April 2017 to March 2023: Results from the First Six Years of a National Surveillance Programme.

Olivia D Conroy, Andrea Mazzella, Hannah Choi, Jocelyn Elmes, Matt Wilson, Dimple Y Chudasama, Sarah M Gerver, Miroslava Mihalkova, Andrew Rhodes, A Peter R Wilson and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Olivia D ConroyCity of Wolverhampton Council, Wolverhampton WV1 1SH, UK.
Andrea MazzellaUK Health Security Agency, London E14 4PU, UK.ORCID 0000-0003-1560-7465
Hannah ChoiTower Hamlets London Borough Council, London E1 1BJ, UK.ORCID 0000-0001-9391-9697
Jocelyn ElmesUK Health Security Agency, London E14 4PU, UK.
Matt WilsonUK Health Security Agency, London E14 4PU, UK.ORCID 0009-0003-4815-7699
Dimple Y ChudasamaUK Health Security Agency, London E14 4PU, UK.
Sarah M GerverUK Health Security Agency, London E14 4PU, UK.
Miroslava MihalkovaUK Health Security Agency, London E14 4PU, UK.
Andrew RhodesSt. George's Hospital, London SW17 0QT, UK.
A Peter R WilsonDepartment of Microbiology, University College London Hospitals, London NW1 2BU, UK.ORCID 0000-0002-6865-3994
Nicholas BrownCambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.ORCID 0000-0002-6657-300X
Jasmin IslamUK Health Security Agency, London E14 4PU, UK.
Russell HopeUK Health Security Agency, London E14 4PU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients in critical care units (CCUs) are at an increased risk of bloodstream infections (BSIs), which can be associated with central vascular catheters (CVCs). This study describes BSIs, CVC-BSIs, organism distribution, percentage of antimicrobial resistant (AMR) organisms, and case fatality rates (CFRs) over the first six years of a voluntary national CCU surveillance programme in England.

methodsSurveillance data on BSIs, CVCs, and bed-days between 04/2017 and 03/2023 for adult CCUs were linked to mortality and AMR data, and crude rates were calculated.

resultsThe rates of CCU-BSIs and CCU-CVC-BSIs were stable for the first three years (3.6 and 1.7 per 1000 bed-days in 2019/20), before increasing by 75% and 94% in 2020/21, respectively, and returning to near pre-pandemic levels by 2022/23. Gram-negative bacteria accounted for 50.3% of all CCU-BSIs, followed by Gram-positive bacteria (39.6%) and

conclusionsBSI incidence in CCUs remained stable across the study period, except for an increase in 2020/21 which reverted by 2022/23. These data provide a benchmark for CCUs and give insight into long-term AMR patterns where comparable national data are limited.

Indexed as

antibiotic resistancebacteremiabloodstream infectioncase-fatality ratecentral venous catheterscritical careEnglandpublic health surveillance

Identifiers

PMID39858951
PMCPMC11767419

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.