Evidence map›Paper›PMID 39858913›Full record

ArticleMicroorganisms2025

Diversity and Potential Cross-Species Transmission of Rotavirus A in Wild Animals in Yunnan, China.

Xiang Le, Yinzhu Tao, Binghui Wang, Yutong Hou, Yuting Ning, Junjie Hou, Ruimei Wang, Qian Li, Xueshan Xia

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiang LeFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0009-0009-6180-7100
Yinzhu TaoYunnan Province Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.
Binghui WangYunnan Province Key Laboratory of Public Health and Biosafety, School of Public Health, Kunming Medical University, Kunming 650500, China.
Yutong HouFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.ORCID 0000-0002-8653-7911
Yuting NingFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Junjie HouFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Ruimei WangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Qian LiClinical Medical College, Dali University, Dali 671000, China.
Xueshan XiaFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

Funding

National Key R&D Program of China 2023YFC2307400National Natural Science Foundation of China 82460392The Youth Talent Program of Yunnan "Ten-thousand Talents Program YNWR-QNBJ-2020-089Yunnan Major Scientific and Technological Projects 202202AG050013
6 · The paper itself

Abstract

Rotavirus A (RVA) is the primary enteric pathogen of humans and many other species. However, RVA interspecies transmission remains poorly understood. In this study, we conducted a comprehensive screening and genotyping analysis of RVA in 1706 wild animal samples collected from various regions within Yunnan Province, China. A total of 24 samples, originating from wild boars, rodents, bats, and birds tested positive for RVA. Next generation sequencing and phylogenetic analyses revealed a high degree of genetic diversity and reassortment, particularly for VP4 and VP7. Strains isolated from wild boars and rodents exhibited gene segments with high similarity to those found in humans and other mammalian RVA strains, indicating that RVA may undergo interspecies transmission and reassortment, resulting in novel strains with potential risks for human infection. This study provides critical data for understanding the transmission mechanisms and the RVA host range, and highlights the pivotal role of wildlife in viral evolution and dissemination. These findings have significant implications for public health policies and emphasize the need for enhanced surveillance to prevent interspecies RVA transmission.

Indexed as

interspecies transmissionmammalian rotavirus ARotavirus A

Identifiers

PMID39858913
PMCPMC11767859

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.