Evidence map›Paper›PMID 39858899›Full record

ArticleMicroorganisms2025

Massive Sequencing of V3-V4 Hypervariable Region in Pyogenic Liver Abscesses Reveals the Presence of Unusual Bacteria Not Detected by Classical Culture Methods.

Verónica Fernández-Sánchez, Estibeyesbo Said Plascencia-Nieto, Mónica Alethia Cureño-Díaz, Emilio Mariano Durán-Manuel, Aida Verónica Rodríguez-Tovar, Claudia Camelia Calzada-Mendoza, Clemente Cruz-Cruz, Miguel Ángel Loyola-Cruz, María Elizbeth Álvarez-Sánchez, Juan Carlos Bravata-Alcántara and 10 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Verónica Fernández-SánchezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-9732-2265
Estibeyesbo Said Plascencia-NietoSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Mónica Alethia Cureño-DíazHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-4556-637X
Emilio Mariano Durán-ManuelHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-8985-486X
Aida Verónica Rodríguez-TovarEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-5514-8972
Claudia Camelia Calzada-MendozaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-5893-8566
Clemente Cruz-CruzHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0003-1555-3102
Miguel Ángel Loyola-CruzHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0001-5383-8737
María Elizbeth Álvarez-SánchezLaboratorio de Patogénesis Celular y Molecular Humana y Veterinaria, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico City 03100, Mexico.ORCID 0000-0002-9212-4451
Juan Carlos Bravata-AlcántaraHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-3585-0051
Enzo Vásquez-JiménezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0003-0205-817X
Víctor Hugo Gutiérrez-MuñozHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-0792-4500
Dulce Milagros Razo Blanco-HernándezHospital Juárez de México, Mexico City 07760, Mexico.
Liliana Nicolás-SayagoHospital Juárez de México, Mexico City 07760, Mexico.
Araceli Rojas-BernabéSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-3851-5881
Omar García-HernándezDivisión de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 54090, Mexico.
Erika Gómez-ZamoraHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-0488-7900
Mireya Ruíz-ValdésHospital Juárez de México, Mexico City 07760, Mexico.
Graciela Castro-EscarpulliEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11340, Mexico.ORCID 0000-0002-7496-8247
Juan Manuel Bello-LópezHospital Juárez de México, Mexico City 07760, Mexico.ORCID 0000-0002-9957-3807

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyogenic liver abscesses (PLAs) are serious infections in which doctors often fail in identifying the causative agent due to microbiological limitations. These limitations in detecting uncommon pathogens complicate the treatment and recovery. Molecular techniques, like massive sequencing, enable the detection of uncommon pathogens and highlight the shortcomings of traditional cultures. The aim of this work was to characterise the bacterial composition of PLAs through massive sequencing of the V3-V4 hypervariable region of the

Indexed as

bioinformaticsDNA sequencingpyogenic liver abscessesV3-V4 hypervariable

Identifiers

PMID39858899
PMCPMC11767335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.