Evidence map›Paper›PMID 39858817›Full record

ArticleMicroorganisms2024

Investigating SARS-CoV-2 Neutralising Antibody Response in Sheep.

Milena Samojlović, João R Mesquita, Sérgio Santos-Silva, Malin Neptin, Joakim Esbjörnsson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Milena SamojlovićSystems Virology, Faculty of Medicine, Lund University, 223 62 Lund, Sweden.ORCID 0000-0002-5685-4027
João R MesquitaInstituto de Ciências Biomédicas Abel Salazar, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-8769-8103
Sérgio Santos-SilvaInstituto de Ciências Biomédicas Abel Salazar, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-9742-5643
Malin NeptinSystems Virology, Faculty of Medicine, Lund University, 223 62 Lund, Sweden.ORCID 0000-0002-6930-1720
Joakim EsbjörnssonSystems Virology, Faculty of Medicine, Lund University, 223 62 Lund, Sweden.

Funding

EUGLOHRIA Research seeding grant 2023FCT Maria de Sousa scholarship 2021.09461.BDRoyal Physiographic Society of Lund The Fund of the Hedda and John Forssman Foundation (application 44104)
6 · The paper itself

Abstract

SARS-CoV-2 can cause clinical and inapparent disease and mortality in several animals cohabitating with humans, and sheep are susceptible to SARS-CoV-2 due to virus-receptor interactions similar to those in humans. Hence, sheep have the potential to be infected, spread, and develop neutralising antibodies (NAbs) against SARS-CoV-2. The aim of this study was to investigate the prevalence of SARS-CoV-2 NAbs in farm animals after natural exposure to the virus. Serum samples were collected from sheep in the Serra da Estrela region in Portugal, both prior to and during the COVID-19 pandemic. The sera were tested by established SARS-CoV-2 pseudovirus systems for multiple SARS-CoV-2 variants (early-Wuhan, mid-Delta, Omicron-BA.1, and late-Omicron XBB, BQ.1.1). Partial neutralisation activity in Pre-pandemic and Mid-pandemic samples was observed, while no NAb activity was observed in Late-pandemic samples tested. Different levels of NAbs were observed between Pre-pandemic samples and those collected during the Mid-pandemic and Late-pandemic periods (

Indexed as

one health approachpandemic preparednessSARS-CoV-2sentinelssheep

Identifiers

PMID39858817
PMCPMC11767788

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.