Evidence map›Paper›PMID 39858771›Full record

ArticleMicroorganisms2024

Determination of the De Novo Minimum Selection Concentration of Trimethoprim In Vivo for

Jaime Knox Macleod, Zina Gestels, Said Abdellati, Thibaut Vanbaelen, Chris Kenyon, Sheeba Santhini Manoharan-Basil

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaime Knox MacleodSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Zina GestelsSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0001-8790-3517
Said AbdellatiSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-9620-8257
Thibaut VanbaelenSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Chris KenyonSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-2557-8998
Sheeba Santhini Manoharan-BasilSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0001-8421-5137

Funding

SOFI 2021 grant-"PReventing the Emergence of untreatable STIs via radical Prevention" (PRESTIP). SOFI 2021
6 · The paper itself

Abstract

We investigated whether the maximum residual levels of trimethoprim permitted in food (Acceptable Daily Intake-ADI) could select for de novo trimethoprim resistance in

Indexed as

AMRantimicrobial consumptionEscherichia coliminimum selection concentrationMSCresistancetrimethoprim

Identifiers

PMID39858771
PMCPMC11767374

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.