Evidence map›Paper›PMID 39858738›Full record

ArticleMicromachines2025

Efficient Particle Manipulation Using Contraction-Expansion Microchannels Embedded with Hook-Shaped Arrays.

Di Huang, Yan Zhao, Chao Cao, Jiyun Zhao

Abstract read
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Di HuangSchool of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, China.ORCID 0000-0003-0843-2855
Yan ZhaoSchool of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, China.
Chao CaoSchool of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, China.
Jiyun ZhaoSchool of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, China.

Funding

National Natural Science Foundation of China 52105596Natural Science Foundation of Jiangsu Province BK20210496
6 · The paper itself

Abstract

Inertial microfluidics, as an efficient method for the manipulation of micro-/nanoparticles, has garnered significant attention due to its advantages of high throughput, structural simplicity, no need for external fields, and sheathless operation. Common structures include straight channels, contraction-expansion array (CEA) channels, spiral channels, and serpentine channels. In this study, we developed a CEA channel embedded with hook-shaped microstructures to modify the characteristics of vortices. Through experimental studies, we investigated the particles' migration mechanisms within the proposed structure. The findings indicated that, in comparison to conventional rectangular microstructures, the particles within the hook-shaped microstructured CEA channels experienced a more pronounced influence from inertial lift forces. Moreover, the magnitude of the second flow within the novel configuration was directly proportional to the channel width, the length of the expansion segment, and the embedding depth of the microstructure. The innovative structure was subsequently employed for particle trapping, focusing, and separation. The experimental outcomes revealed focusing efficiency of up to 99.1% and sorting efficiency of up to 97%. This research holds the potential to enhance the foundational theory of Dean flows and broaden the application spectrum of inertial contraction-expansion microfluidic chips.

Indexed as

contraction–expansion array microchannelhook-shaped arraysinertial migrationmicrofluidics

Identifiers

PMID39858738
PMCPMC11767759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.