Evidence map›Paper›PMID 39858651›Full record

ArticleGenes2025

The Epigenetic Machinery and Energy Expenditure: A Network to Be Revealed.

Elisabetta Prada, Giulia Bruna Marchetti, Denise Pires Marafon, Alessandra Mazzocchi, Giulietta Scuvera, Lidia Pezzani, Carlo Agostoni, Donatella Milani

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisabetta PradaAzienda Socio Sanitaria Territoriale Lariana, 22100 Como, Italy.
Giulia Bruna MarchettiFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Denise Pires MarafonDepartment of Public Health and Infectious Diseases, Specialization School in Medical Statistics and Biometry, Università Sapienza di Roma, 00185 Roma, Italy.
Alessandra MazzocchiFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0003-0291-2874
Giulietta ScuveraFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Lidia PezzaniFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Carlo AgostoniFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0002-5006-0832
Donatella MilaniFondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.ORCID 0000-0002-3087-8514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mendelian disorders of the epigenetic machinery (MDEMs) include a large number of conditions caused by defective activity of a member of the epigenetic machinery. MDEMs are characterized by multiple congenital abnormalities, intellectual disability and abnormal growth. that can be variably up- or down-regulated.

Indexed as

Energy MetabolismEpigenesis, GeneticAdolescentAdultChildChild, PreschoolFemaleHumansMaleMetabolic SyndromeObesitychromatinopathiesmetabolismrest energy expenditureRubinstein–Taybisotos

Identifiers

PMID39858651
PMCPMC11764581

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.