Evidence map›Paper›PMID 39858641›Full record

ArticleGenes2025

Casein Kinase I Protein Hrr25 Is Required for Pin4 Phosphorylation and Mediates Cell Wall Integrity Signaling in

Amita Bhattarai, Manika Bhondeley, Zhengchang Liu

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pelletized Growth inJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amita BhattaraiDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.
Manika BhondeleyDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.ORCID 0000-0003-4102-1943
Zhengchang LiuDepartment of Biological Sciences, University of New Orleans, New Orleans, LA 70148, USA.ORCID 0000-0002-8039-0998

Funding

Regulation of Mitochondrial Biogenesis in YeastR15GM121998 · NIGMS · UNIVERSITY OF NEW ORLEANS · PI LIU, ZHENGCHANG · 2016 to 2016
$347k
NIGMS NIH HHS R15 GM121998NIH HHS 1R15GM121998-01
6 · The paper itself

Abstract

backgroundCasein kinase I protein Hrr25 plays important roles in many cellular processes, including autophagy, vesicular trafficking, ribosome biogenesis, mitochondrial biogenesis, and the DNA damage response in METHODS/

objectivesCo-immunoprecipitation and yeast two-hybrid assays were utilized to confirm whether Pin4 and Hrr25 interact and to determine how they interact. Genetic interaction analysis was conducted to examine whether

resultsWe show that Hrr25 interacts with Pin4 and is required for Pin4 phosphorylation.

conclusionsOur data suggest that Hrr25 is implicated in cell wall integrity signaling via its association with Pin4.

Indexed as

Casein Kinase ICell WallSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsMutationPhosphorylationSignal TransductionCasein Kinase IHRR25 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsBck1casein kinase Icell wall integrityHrr25Pin4protein phosphorylationRlm1Slt2

Identifiers

PMID39858641
PMCPMC11765155

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.