Evidence map›Paper›PMID 39858475›Full record

ReviewBiomolecules2025

Utilizing Feature Selection Techniques for AI-Driven Tumor Subtype Classification: Enhancing Precision in Cancer Diagnostics.

Jihan Wang, Zhengxiang Zhang, Yangyang Wang

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jihan WangYan'an Medical College of Yan'an University, Yan'an 716000, China.
Zhengxiang ZhangYan'an Medical College of Yan'an University, Yan'an 716000, China.
Yangyang WangSchool of Electronics and Information, Northwestern Polytechnical University, Xi'an 710129, China.

Funding

the Open Funds for Shaanxi Provincial Key Laboratory of Infection and Immune Diseases 2023-KFMS-1
6 · The paper itself

Abstract

Cancer's heterogeneity presents significant challenges in accurate diagnosis and effective treatment, including the complexity of identifying tumor subtypes and their diverse biological behaviors. This review examines how feature selection techniques address these challenges by improving the interpretability and performance of machine learning (ML) models in high-dimensional datasets. Feature selection methods-such as filter, wrapper, and embedded techniques-play a critical role in enhancing the precision of cancer diagnostics by identifying relevant biomarkers. The integration of multi-omics data and ML algorithms facilitates a more comprehensive understanding of tumor heterogeneity, advancing both diagnostics and personalized therapies. However, challenges such as ensuring data quality, mitigating overfitting, and addressing scalability remain critical limitations of these methods. Artificial intelligence (AI)-powered feature selection offers promising solutions to these issues by automating and refining the feature extraction process. This review highlights the transformative potential of these approaches while emphasizing future directions, including the incorporation of deep learning (DL) models and integrative multi-omics strategies for more robust and reproducible findings.

Indexed as

Artificial IntelligenceNeoplasmsAlgorithmsBiomarkers, TumorHumansMachine LearningPrecision MedicineBiomarkers, Tumorartificial intelligencebiomarkersdeep learningfeature selectionhigh-dimensional datamachine learningmulti-omicstumor subtype classification

Identifiers

PMID39858475
PMCPMC11763904

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.