ReviewBiomolecules2025
The Metabolism of Creatinine and Its Usefulness to Evaluate Kidney Function and Body Composition in Clinical Practice.
Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Curcumin/Turmeric Supplementation on Kidney Function in Individuals With Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Endocrinology, diabetes & metabolism · 2026Pooled it
- Multicomponent Online Intervention Improves Sarcopenia-Related Traits Following Long-Term Metabolic Bariatric Surgery: A Randomized Clinical Trial.Obesity surgery · 2026Trial
- Hydroxyurea interferes with point-of-care creatinine testing in children with sickle cell anemia.BMC research notes · 2026Trial
- Age- and sex-specific serum creatinine reference curves in children and adolescents with Down syndrome.European journal of pediatrics · 2026Article
- Effects of graded dietary raw bee venom inclusion on growth, immunity, and disease resistance in Nile tilapia (Oreochromis niloticus).Scientific reports · 2026Article
- Comparative machine learning modeling of resting energy expenditure estimation in mechanically ventilated children after cardiac surgery.European journal of clinical nutrition · 2026Article
- Plasma Multi-Metal Exposure, Renal Function, and Anemia Risk in Rural China: The Mediating Role of Serum Creatinine.Biological trace element research · 2026Article
- Evaluation of Haemato-Biochemical and Physiological Parameters of Different Dairy Breeds During the Dry and Wet Seasons in Central Ethiopia.Veterinary medicine and science · 2026Article
- Predictive value of the albumin-to-creatinine and bicarbonate-to-lactate ratios for 28-day mortality in acute mesenteric ischemia.Turkish journal of surgery · 2026Article
- Association between serum albumin levels and constipation prevalence: a cross-sectional analysis of NHANES 2005-2010 data.Irish journal of medical science · 2026Article
- Plasma Erythropoietin Levels and Anemia in Vietnamese Patients With Type 2 Diabetes and Chronic Kidney Disease: 2018-2019.Health science reports · 2026Article
- A Simple Admission-Based Score for Early Mortality Risk Stratification in Non-Shock Sepsis: A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Cardiorenal Biomarkers and their Implications in Prognosis and Treatment Response of Transthyretin Cardiac Amyloidosis.Current heart failure reports · 2026Review
- Gut microbiota-metabolite interactions in cisplatin-induced acute kidney injury in rats.BMC microbiology · 2026Article
- Beyond Numbers: CKD-EPI Versus MDRD in Primary Care-Differences in Chronic Kidney Disease Stage Classification in 117,055 Patients.Journal of clinical medicine · 2026Article
- Human Serum Albumin-Lipid Nanocapsules of Duvelisib for Hematological Cancers: Characterization, In-Vitro Cell-Culture, Toxicity and Pharmacokinetic Studies.AAPS PharmSciTech · 2026Article
- Admission eGFR as a Marker of Systemic Vulnerability in Patients with Spontaneous Intracerebral Hemorrhage: Impact of Premorbid Disability and Acute Kidney Injury on Outcomes.Journal of clinical medicine · 2026Article
- The mediating effect of triglycerides and related indices on the association between polycyclic aromatic hydrocarbons and oral health in adults aged ≥ 45 years from the national health and nutrition examination survey 2003-2016.Lipids in health and disease · 2026Article
- Polyphenol-enriched fraction ofFrontiers in pharmacology · 2026Article
- Plasma asymmetric dimethylarginine and its association with cardiovascular risk factors in Vietnamese patients before and after kidney transplantation, 2018-2022.Frontiers in nephrology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serum creatinine levels are the most used clinical marker to estimate renal function as the glomerular function rate because it is simple, fast, and inexpensive. However, creatinine has limitations, as its levels can be influenced by factors such as advanced age, physical activity, protein-rich diets, male gender, medications, and ethnicity. Serum cystatin C and its combination with serum creatinine may serve as an alternative since these factors do not affect it. Most creatinine synthesis occurs in the muscles, making it a valuable marker for assessing lean body mass within body composition. This measurement is crucial for evaluating and monitoring nutritional status in patients with chronic kidney disease. This review aimed to discuss the literature on creatinine metabolism, its advantages and disadvantages in assessing renal function, and its utility in measuring lean body mass. The variability in the creatinine generation rate among individuals should be considered when assessing the glomerular function rate.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.