ArticleAnimals : an open access journal from MDPI2025
Immunohistochemical Expression of Vascular Endothelial Growth Factor (VEGF) in Primary Canine Mast Cell Tumors and Related Regional Lymph Node Metastasis.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Association of Blood Plasma Vascular Endothelial Growth Factor and Testicular Artery Doppler Parameters with Canine Sperm Freezability.Animals : an open access journal from MDPI · 2026Article
- Gene Expression of Hormone Receptors and Growth Factors in Intact and Neutralized Female Dogs, Both Healthy and with Cutaneous Mast Cell Tumors.Animals : an open access journal from MDPI · 2026Article
- Survival analysis of different treatment modalities and associated outcomes for canine primary pulmonary carcinoma.Frontiers in veterinary science · 2026Article
- Correction: Corrêa Rassele et al. Immunohistochemical Expression of Vascular Endothelial Growth Factor (VEGF) in Primary Canine Mast Cell Tumors and Related Regional Lymph Node Metastasis.Animals : an open access journal from MDPI · 2025Article
- Comparative pathophysiology and molecular insights into cutaneous and non-cutaneous canine skin cancers: focus on melanoma, mast cell tumors, and squamous cell carcinoma.Frontiers in immunology · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis and has been identified as an autocrine growth factor for neoplastic cells of several tumors. The aim of this study was to evaluate VEGF expression in canine mast cell tumors and their respective lymph node metastases. For this purpose, 28 patients with mast cell tumors and confirmed regional lymph node metastasis were selected. The samples were submitted for analysis with immunohistochemistry. VEGF was expressed in 14/28 patients (50%) and 35.7% of primary MCTs (10/28), and only 14.3% expressed VEGF in both the primary tumor and its respective metastasis (4/28), with fair agreement (Κ = 0.250). There was a weak correlation between VEGF and tumor size (
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Registered trials
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