Evidence map›Paper›PMID 39858067›Full record

ArticleCancers2025

Enhanced Lung Cancer Survival Prediction Using Semi-Supervised Pseudo-Labeling and Learning from Diverse PET/CT Datasets.

Mohammad R Salmanpour, Arman Gorji, Amin Mousavi, Ali Fathi Jouzdani, Nima Sanati, Mehdi Maghsudi, Bonnie Leung, Cheryl Ho, Ren Yuan, Arman Rahmim

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammad R SalmanpourBC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.
Arman GorjiTechnological Virtual Collaboration (TECVICO Corp.), Vancouver, BC V6L 1L7, Canada.ORCID 0009-0009-0728-9787
Amin MousaviTechnological Virtual Collaboration (TECVICO Corp.), Vancouver, BC V6L 1L7, Canada.ORCID 0009-0009-0232-3587
Ali Fathi JouzdaniTechnological Virtual Collaboration (TECVICO Corp.), Vancouver, BC V6L 1L7, Canada.
Nima SanatiTechnological Virtual Collaboration (TECVICO Corp.), Vancouver, BC V6L 1L7, Canada.ORCID 0009-0007-2577-1863
Mehdi MaghsudiTechnological Virtual Collaboration (TECVICO Corp.), Vancouver, BC V6L 1L7, Canada.ORCID 0000-0001-6844-3850
Bonnie LeungBC Cancer, Vancouver Center, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0003-3319-8343
Cheryl HoBC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0002-5922-3984
Ren YuanDepartment of Radiology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.ORCID 0000-0001-5127-7841
Arman RahmimBC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0002-9980-2403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study explores a semi-supervised learning (SSL), pseudo-labeled strategy using diverse datasets such as head and neck cancer (HNCa) to enhance lung cancer (LCa) survival outcome predictions, analyzing handcrafted and deep radiomic features (HRF/DRF) from PET/CT scans with hybrid machine learning systems (HMLSs).

methodsWe collected 199 LCa patients with both PET and CT images, obtained from TCIA and our local database, alongside 408 HNCa PET/CT images from TCIA. We extracted 215 HRFs and 1024 DRFs by PySERA and a 3D autoencoder, respectively, within the ViSERA 1.0.0 software, from segmented primary tumors. The supervised strategy (SL) employed an HMLS-PCA connected with six classifiers on both HRFs and DRFs. The SSL strategy expanded the datasets by adding 408 pseudo-labeled HNCa cases (labeled by the Random Forest algorithm) to 199 LCa cases, using the same HMLS techniques. Furthermore, principal component analysis (PCA) linked with four survival prediction algorithms were utilized in the survival hazard ratio analysis.

resultsThe SSL strategy outperformed the SL method (

conclusionsShifting from HRFs and SL to DRFs and SSL strategies, particularly in contexts with limited data points, enabling CT or PET alone, can significantly achieve high predictive performance.

Indexed as

deep and handcrafted radiomic featureslung cancermachine learningsupervised and semi-supervised strategysurvival prediction

Identifiers

PMID39858067
PMCPMC11763441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.