Evidence map›Paper›PMID 39858032›Full record

ReviewCancers2025

Diagnosis and Management of Skin Toxicities in Systemic Treatment of Genitourinary Cancers.

Deepro Chowdhury, Laura Chin, Roupen Odabashian, Ali Fawaz, Christina Canil, Michael Ong, Mark G Kirchhof, Martin Neil Reaume, Ana-Alicia Beltran-Bless, Marie-France Savard and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Deepro ChowdhuryDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Laura ChinDivision of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-3640-1282
Roupen OdabashianDepartment of Oncology, Wayne State University, Detroit, MI 48202, USA.
Ali FawazDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Christina CanilDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Michael OngDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Mark G KirchhofDivision of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Martin Neil ReaumeDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Ana-Alicia Beltran-BlessDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0003-4880-8167
Marie-France SavardDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-7651-0870
David J TsoulisDivision of Dermatology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.
Dominick BosséDivision of Oncology, Department of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0003-2992-5632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The landscape of available therapeutic options for treatment of genitourinary (GU) cancers is expanding dramatically. Many of these treatments have distinct, sometimes severe, skin toxicities including morbilliform, bullous, pustular, lichenoid, eczematous, psoriasiform, and palmoplantar eruptions. Pruritus and skin pigmentation changes have also been noted. This review aims to synthesize dermatologic events observed with antibody drug conjugates, poly (ADP-ribose) polymerase (PARP) inhibitors, androgen receptor pathway inhibitors, tyrosine kinase inhibitors, immune checkpoint inhibitors, and the combination of these agents used for the treatment of GU cancers. It provides a guide on diagnosis and initial management of these rashes for medical oncologists.

Indexed as

genitourinary cancersimmunotherapyprostate cancerrashrenal cell carcinomaskin disordersStevens–Johnson syndromeurothelial carcinoma

Identifiers

PMID39858032
PMCPMC11763385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.