Evaluation of Individual Cardiovascular Risk in Pre-Dialysis CKD Patients by Using the Ratio of Calcium-Phosphorus Product to Estimated Glomerular Filtration Rate (Ca × P/eGFR).

Krasimir Kostov, Tatyana Simeonova, Borislav Ignatov, Tsvetelina Eftimova

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Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Krasimir KostovDepartment of Physiology and Pathophysiology, Medical University-Pleven, 1 Kliment Ohridski Str., 5800 Pleven, Bulgaria.ORCID 0000-0003-2464-353X

Tatyana SimeonovaDepartment of Physiology and Pathophysiology, Medical University-Pleven, 1 Kliment Ohridski Str., 5800 Pleven, Bulgaria.ORCID 0000-0002-2307-1229

Borislav IgnatovDepartment of Physiology and Pathophysiology, Medical University-Pleven, 1 Kliment Ohridski Str., 5800 Pleven, Bulgaria.ORCID 0000-0002-0325-6162

Tsvetelina EftimovaHemodialysis Unit, St. Marina Hospital, 5800 Pleven, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) patients have an increased risk of cardiovascular disease (CVD), necessitating effective risk assessment methods. This study evaluates the calcium-phosphorus product (Ca × P) to estimated glomerular filtration rate (Ca × P/eGFR) ratio as a potential biomarker for predicting CV risk in pre-dialysis CKD patients.

methodsEighty-four CKD patients in stages G1-G4, according to the KDIGO criteria, were classified into CVD (

resultsSignificant differences were observed in SCr, BUN, eGFR (

conclusionsThe Ca × P/eGFR ratio may serve as a significant predictor of CVD risk in pre-dialysis CKD patients, suggesting that its integration into routine evaluations could enhance CV risk stratification and management.

Indexed as

biomarkers of kidney functioncardiorenal syndrome type 4cardiovascular riskchronic kidney disease

Identifiers

PMID39857818

DOI10.3390/biomedicines13010235

PMCPMC11762089

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