Evidence map›Paper›PMID 39857696›Full record

ArticleBiomedicines2025

MicroRNAs Expression Profile in MN1-Altered Astroblastoma.

Francesca Gianno, Evelina Miele, Claudia Sabato, Elisabetta Ferretti, Simone Minasi, Francesca Romana Buttarelli, Debora Salerno, Natalia Pediconi, Giuseppe Rubens Pascucci, Francesca Guerrieri and 14 more

Abstract read
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In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Francesca GiannoDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, University Sapienza of Rome, 00161 Rome, Italy.ORCID 0000-0002-6223-9952
Evelina MieleHematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-4747-1032
Claudia SabatoDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-7533-4660
Elisabetta FerrettiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-7265-6429
Simone MinasiDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, University Sapienza of Rome, 00161 Rome, Italy.ORCID 0000-0002-8872-6409
Francesca Romana ButtarelliDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, University Sapienza of Rome, 00161 Rome, Italy.ORCID 0000-0001-5892-1281
Debora SalernoDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Natalia PediconiCenter for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), 16161 Rome, Italy.
Giuseppe Rubens PascucciResearch Unit of Clinical Immunology and Vaccinology, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Francesca GuerrieriUMR INSERM U1052/CNRS 5286, Cancer Research Center of Lyon, 69008 Lyon, France.
Andrea CiolfiMolecular Genetics and Functional Genomics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Simone PizziInstitute of Biosciences and Bioresources, National Research Council, 06128 Perugia, Italy.
Maura MassiminoPediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milano, Italy.ORCID 0000-0002-5506-2001
Veronica BiassoniPediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milano, Italy.ORCID 0000-0003-1486-1736
Elisabetta SchiavelloPediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milano, Italy.
Marco GessiDepartment of Woman and Child Health Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Sofia AsioliIRCCS Istituto di Scienze Neurologiche di Bologna, 40139 Bologna, Italy.ORCID 0000-0002-5035-2448
Angela MastronuzziHematology/Oncology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, 586724 Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-4408-2373
Antonio d'AmatiDepartment of Basic Medical Sciences, Neuroscience, and Sensory Organs, University of Bari School of Medicine, 70121 Bari, Italy.ORCID 0000-0002-4810-1201
Giuseppina CatanzaroDepartment of Life Science, Health, and Health Professions, Link Campus University, 00165 Rome, Italy.ORCID 0000-0001-8427-9691
Elisabetta ViscardiPediatric Oncology Unit, Padova University, 35122 Padova, Italy.
David CapperCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt, 10117 Berlin, Germany.
Felice GiangasperoDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, University Sapienza of Rome, 00161 Rome, Italy.ORCID 0000-0001-5382-2380
Manila AntonelliDepartment of Radiological, Oncological and Anatomo-Pathological Sciences, University Sapienza of Rome, 00161 Rome, Italy.

Funding

Associazione Italiana per la Lotta al Neuroblastoma No grant number
6 · The paper itself

Abstract

BACKGROUND/

objectivesAstroblastoma is a rare glial neoplasm more frequent in young female patients, with unclear clinical behaviors and outcomes. The diagnostic molecular alteration is a rearrangement of the Meningioma 1 (

methodsA cohort of 14 tumor samples, histologically classified as astroblastoma, was retrospectively collected and analyzed through their DNA methylation profiles. MiRNA expression profiles were then detected on

resultsEight

conclusions

Indexed as

astroblastomabiological processesepigeneticmethylationmicroRNAmiRNA expressionMN1 rearrangement

Identifiers

PMID39857696
PMCPMC11762140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.