Evidence map›Paper›PMID 39857648›Full record

ReviewBiomedicines2024

Nitrate-Nitrite-Nitric Oxide Pathway, Oxidative Stress, and Fertility Outcomes in Morbidly Obese Women Following Bariatric Surgery: A Systematic Review.

Charalampos Voros, Despoina Mavrogianni, Aspasia Minaoglou, Alexios Karakasis, Anthi-Maria Papahliou, Vasileios Topalis, Antonia Varthaliti, Raphail Mantzioros, Panagiota Kondili, Menelaos Darlas and 4 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Unlocking Implantation: The Role of Nitric Oxide, NOInternational journal of molecular sciences · 2025
    Pooled it
  3. Article
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  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charalampos Voros1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0000-0001-9477-7619
Despoina Mavrogianni1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0000-0003-1220-6594
Aspasia Minaoglou1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0009-0008-2571-871X
Alexios Karakasis1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.
Anthi-Maria Papahliou1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.
Vasileios TopalisDepartment of Internal Medicine, Hospital of Thun, 3600 Thun, Switzerland.
Antonia Varthaliti1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0009-0008-8725-7103
Raphail Mantzioros1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0009-0007-7647-974X
Panagiota Kondili1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.
Menelaos Darlas1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.
Regina Sotiropoulou1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.
Diamantis AthanasiouIVF Athens Reproduction Center V. Athanasiou, 15123 Maroussi, Greece.
Dimitrios LoutradisFertility Institute-Assisted Reproduction Unit, Paster 15, 11528 Athens, Greece.ORCID 0000-0002-8686-594X
Georgios Daskalakis1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens, 80 Vasilissis Sofias Avenue, 11528 Athens, Greece.ORCID 0000-0001-7108-211X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity reduces nitric oxide (NO) production due to endothelial nitric oxide synthase (eNOS) dysfunction, resulting in oxidative stress, mitochondrial dysfunction, and chronic inflammation. These factors have a negative impact on reproductive health, including oocyte quality, endometrial receptivity, and embryo implantation. When oxidative stress affects eNOS function, the nitrate-nitrite-nitric oxide (NO

Indexed as

bariatricsendothelial nitric oxide synthase (eNOS)infertilitynitric oxide (NO)obesityoxidative stress

Identifiers

PMID39857648
PMCPMC11762565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.