Evidence map›Paper›PMID 39857438›Full record

ReviewAntioxidants (Basel, Switzerland)2025

Role of Oxidative Stress in the Occurrence, Development, and Treatment of Breast Cancer.

Rui Dong, Jing Wang, Ruiqi Guan, Jianwei Sun, Ping Jin, Junling Shen

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The GATA3-RFPL3-ASK1 axis suppresses breast cancer growth and lung metastasis.Apoptosis : an international journal on programmed cell death · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Anticancer and Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  15. Review
  16. Frontiers in pharmacology · 2026
    Article
  17. Polyphenol-enriched fraction ofFrontiers in pharmacology · 2026
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rui DongYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
Jing WangYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
Ruiqi GuanYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
Jianwei SunYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
Ping JinYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
Junling ShenYunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.

Funding

grant from Key Laboratory of Tumor Immunological Prevention and Treatment in Yunnan Province Grant No. KLTIPT-2023-02National Natural Science Foundation of China 32260167National Natural Science Foundation of China 82273460National Natural Science Foundation of China 82303506Yan'an Hospital Affiliated Kunming Medical University, Kunming and grants KC-23234451Yan'an Hospital Affiliated Kunming Medical University, Kunming and grants ZC-24249243Yunnan Fundamental Research Projects 202401AS070133Yunnan Fundamental Research Projects 202401CF070184
6 · The paper itself

Abstract

Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.

Indexed as

breast cancerdrug resistanceoxidative stressreactive oxygen species (ROS)therapeutic strategies

Identifiers

PMID39857438
PMCPMC11760893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.