Evidence map›Paper›PMID 39857408›Full record

ReviewAntioxidants (Basel, Switzerland)2025

The Role of Polyphenols in Abiotic Stress Tolerance and Their Antioxidant Properties to Scavenge Reactive Oxygen Species and Free Radicals.

Muhammad Junaid Rao, Bingsong Zheng

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Evaluation of Sesame (Plants (Basel, Switzerland) · 2026
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  19. Multi-Targeted Neuroprotection byInternational journal of molecular sciences · 2026
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Muhammad Junaid RaoState Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.ORCID 0000-0003-4911-9451
Bingsong ZhengState Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.ORCID 0000-0001-6185-5641

Funding

Key Funded Project of Zhejiang 151 Talent Engineering (for Bingsong Zheng) 151Overseas Expertise Introduction Project for Discipline Innovation (111 Project D18008). D18008
6 · The paper itself

Abstract

Plants have evolved complex mechanisms to cope with diverse abiotic stresses, with the phenylpropanoid pathway playing a central role in stress adaptation. This pathway produces an array of secondary metabolites, particularly polyphenols, which serve multiple functions in plant growth, development, regulating cellular processes, and stress responses. Recent advances in understanding the molecular mechanisms underlying phenylpropanoid metabolism have revealed complex regulatory networks involving MYB transcription factors as master regulators and their interactions with stress signaling pathways. This review summarizes our current understanding of polyphenol-mediated stress adaptations in plants, emphasizing the regulation and function of key phenylpropanoid pathway compounds. We discussed how various abiotic stresses, including heat and chilling stress, drought, salinity, light stress, UV radiation, nanoparticles stress, chemical stress, and heavy metal toxicity, modulate phenylpropanoid metabolism and trigger the accumulation of specific polyphenolic compounds. The antioxidant properties of these metabolites, including phenolic acids, flavonoids, anthocyanins, lignin, and polyphenols, and their roles in reactive oxygen species scavenging, neutralizing free radicals, membrane stabilization, and osmotic adjustment are discussed. Understanding these mechanisms and metabolic responses is crucial for developing stress-resilient crops and improving agricultural productivity under increasingly challenging environmental conditions. This review provides comprehensive insights into integrating phenylpropanoid metabolism with plant stress adaptation mechanisms, highlighting potential targets for enhancing crop stress tolerance through metabolic adjustment.

Indexed as

abiotic stress tolerancebioactive moleculesflavonoidsfree radicalsMYB regulatory factorsphenylpropanoid pathwaypolyphenolsreactive oxygen species

Identifiers

PMID39857408
PMCPMC11761259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.